Computer aided vaccine design 1st Edition by Tong Joo Chuan, Shoba Ranganathan 9781907568411 1907568417
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Product details:
ISBN 10: 1907568417
ISBN 13: 9781907568411
Author: Tong Joo Chuan, Shoba Ranganathan
Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates.
Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use. Chapters include: MHC and T cell responses; Immunoglobulins and B cell responses; Scientific publications and databases; Database design; Computational T cell vaccine design; Computational B cell vaccine design; infectious disease informatics; Vaccine safety and quality assessments; and Vaccine adjuvant informatics.
- Essential reading for any biologist who wants to understand methods of computer-aided vaccine design
- Description of available data sources and publicly available software, with detailed analysis of strengths and weaknesses
- Theoretical concepts and practical examples of database design and development for a virtual screening campaign
Table of contents:
Chapter 1 MHC and T Cell Responses
Chapter 2 Immunoglobulins and B Cell Responses
Chapter 3 Scientific Publications and Databases
Chapter 4 Database Design
Chapter 5 Computational T Cell Vaccine Design
Chapter 6 Computational B Cell Vaccine Design
Chapter 7 Infectious Disease Informatics
Chapter 8 Vaccine Safety and Quality Assessments
Chapter 9 Vaccine Adjuvant Informatics
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Tags: Tong Joo Chuan, Shoba Ranganathan, Computer, design