Applications of Ion Chromatography for Pharmaceutical and Biological Products 1st Edition by Lokesh Bhattacharyya, Jeffrey Rohrer – Ebook PDF Instant Download/Delivery: 9780470467091, 0470467096
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Product details:
ISBN 10: 0470467096
ISBN 13: 9780470467091
Author: Lokesh Bhattacharyya, Jeffrey S. Rohrer
This is a comprehensive source of information on the application of ion chromatography (IC) in the analysis of pharmaceutical drugs and biologicals. This book, with contributors from academia, pharma, the biotech industry, and instrument manufacturing, presents the different perspectives, experience, and expertise of the thought leaders of IC in a comprehensive manner. It explores potential IC applications in different aspects of product development and quality control testing. In addition, an appendix section gives information on critical physical and chromatographic parameters related to IC and information on current manufacturers of IC systems, columns, and other components.
Table of contents:
Part I : Principles, Mechanism, and Instrumentation
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Chapter 1: Ion Chromatography—Principles and Applications
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Chapter 2: Retention Processes in Ion-Exclusion Chromatography: A New Perspective
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Chapter 3: Pulsed Electrochemical Detection in Ion Chromatography
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Chapter 4: Suppressor Design and Detection for Ion Chromatography
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Chapter 5: Modelling and Optimization of Ion Chromatographic Separations of Pharmaceutically Relevant Organic Ions
Part II : Pharmaceutical Applications
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Chapter 6: Ion Chromatography in Pharmaceutical Drug Analysis
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Chapter 7: Analysis for Impurities by Ion Chromatography
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Chapter 8: Ion Chromatography Analysis of Aminoglycoside Antibiotics
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Chapter 9: Use of Cation-Exchange Ion Chromatography in the Analysis of Pharmaceuticals
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Chapter 10: Comprehensive Approaches for Measurement of Active Pharmaceutical Ingredients, Counter-Ions, and Excipients Using HPLC with Charged Aerosol Detection
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Chapter 11: High Performance Ion Chromatographic Analysis of Cholinergic Compounds: Carbachol and Bethanechol, and Associated Degradation Products
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Chapter 12: Ion Chromatographic Analysis of Pharmaceuticals for Authenticity and Adulteration
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Chapter 13: Ion Chromatography of Drug Product Counter-Ions and Other Ions in Drug Products
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Chapter 14: Sample Preparation Techniques in Ion Chromatography for Pharmaceutical Applications
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Chapter 15: Validation of Ion Chromatographic Methods
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Chapter 16: Pharmacopeial Applications of Ion Chromatography
Part III : Biotechnology Applications
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Chapter 17: Glycan Analysis by High Performance Anion Exchange Chromatography with Pulsed Amperometric Detection
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Chapter 18: Monosaccharide Analysis of Glycoproteins by High-Performance Anion-Exchange Chromatography with Pulsed Amperometric Detection
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Chapter 19: Two-Dimensional Ion Chromatography for Simultaneous Determination of Amino Acids and Carbohydrates
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Chapter 20: Monitoring Protein N-Glycosylation Consistency Using HPAEC-PAD
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Chapter 21: Oligosaccharide Analysis by High-Performance Anion-Exchange Chromatography Hyphenated to Integrated Pulsed Amperometric Detection and On-Line Ion-Trap Mass Spectrometry
Part IV : Vaccine Applications
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Chapter 22: Applications of Ion Chromatography in Biological Product Analyses
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Chapter 23: HPAEC-PAD Analysis of GBS Glycoconjugate Vaccines: From Fermentation to Final Product
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Chapter 24: Stability Studies and Characterization of Meningococcal A, C, Y, and W135 Glycoconjugate Vaccine
Part V : Appendices
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Appendix 1: Dissociation Constants (pKa) of Organic Acids (at 20°C)
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Appendix 2: Dissociation Constants (pKa) of Common Sugars and Alcohols
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Tags: Lokesh Bhattacharyya, Jeffrey Rohrer, Applications, Pharmaceutical