Neurobiology of Depression 1st Edition by Francisco Lopez Munoz, Cecilio Alamo 1439838496 9781439838495

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ISBN 10: 1439838496

ISBN 13: 9781439838495

Author: Francisco Lopez-Munoz, Cecilio Alamo

Major depressive disorders have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways hold promise as new therapeutics for depression. With the collaboration of the most prestigious international specialists in biochemistry

Neurobiology of Depression 1st Table of contents:

1 Animal Models of Depression

2 Neurophysiological and Neuropsychological Models of Depression

3 Neural Foundations of Major Depression: Classical Approaches and New Frontiers

4 Genetic Regulation of Emotion Brain Circuitries

5 Development of Brain Monoaminergic Systems

6 Contribution of Pharmacology to Development of Monoaminergic Hypotheses of Depression

7 Serotonergic Pathways in Depression

8 Noradrenergic System in Depression

O Glutamatergic System and Mood Disorders

10 Role of the Endocannabinoid System in Etiopathology of Major Depression

11 Opioid System and Depression

12 Chronobiological Rhythms, Melatonergic System, and Depression

13 Corticotropin-Releasing Factor and Hypothalamic-Pituitary-Adrenal Axis Regulation of Behavioral Stress Response and Depression

14 Depression and Cytokine-Regulated Pathways

15 Tachykinins and Tachykinin Receptor Antagonists in Depression: Therapeutic Implications

16 Role of Neuropeptide Y in Depression: Current Status

1 7 Nitric Oxide Signaling in Depression and Antidepressant Action

18 Beta-Arrestins in Depression: A Molecular Switch from Signal Desensitization to Alternative Intracellular Adaptor Functions

19 Brain-Derived Neurotrophic Factor and Major Depression

20 Role of Cyclic Nucleotide Phosphodiesterases in Depression and Antidepressant Activity

21 Vascular Depression: A Neuropsychological Perspective

22 Neurobiological Basis for Development of New Antidepressant Agents

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Francisco Lopez Munoz,Cecilio Alamo,Neurobiology,Depression