Plasmids biology and impact in biotechnology and discovery 1st Edition by Marcelo Tolmasky, Juan Carlos Alonso 9781555818982 1555818986

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Product details:

ISBN 10: 1555818986

ISBN 13: 9781555818982

Author: Marcelo E. Tolmasky, Juan Carlos Alonso

Explore the remarkable discoveries in the rapidly expanding field of plasmid biology Plasmids are integral to biological research as models for innumerable mechanisms of living cells, as tools for creating the most diverse therapies, and as crucial helpers for understanding the dissemination of microbial populations. Their role in virulence and antibiotic resistance, together with the generalization of “omics” disciplines, has recently ignited a new wave of interest in plasmids. This comprehensive book contains a series of expertly written chapters focused on plasmid biology, mechanistic details of plasmid function, and the increased utilization of plasmids in biotechnology and pharmacology that has occurred in the past decade. Plasmids: Biology and Impact in Biotechnology and Discovery serves as an invaluable reference for researchers in the wide range of fields and disciplines that utilize plasmids and can also be used as a textbook for upper-level undergraduate and graduate courses in biotechnology and molecular biology.

Table of contents:

I. Introduction
Chapter 1: Historical Events That Spawned the Field of Plasmid Biology

II. Plasmid Replication Systems and Their Control
Chapter 2: Iteron Plasmids
Chapter 3: Mechanisms of Theta Plasmid Replication
Chapter 4: Plasmid Rolling-Circle Replication
Chapter 5: Replication and Maintenance of Linear Phage-Plasmid N15
Chapter 6: Plasmid Replication Control by Antisense RNAs
Chapter 7: Topological Behavior of Plasmid DNA

III. Plasmid Maintenance, Transfer and Barriers
Chapter 8: Plasmid Partition Mechanisms
Chapter 9: Resolution of Multimeric Forms of Circular Plasmids and Chromosomes
Chapter 10: Conditional Activation of Toxin-Antitoxin Systems: Postsegregational Killing and Beyond
Chapter 11: The Interplay between Different Stability Systems…
Chapter 12: The CRISPR-Cas Immune System and Genetic Transfers…
Chapter 13: Plasmid Diversity and Adaptation Analyzed by Massive Sequencing…
Chapter 14: Conjugation in Gram-Positive Bacteria
Chapter 15: Mobilizable Rolling-Circle Replicating Plasmids from Gram-Positive Bacteria

IV. Specific Plasmid Systems
Chapter 16: The Plasmid Mobilome of the Model Plant-Symbiont Sinorhizobium meliloti
Chapter 17: The Agrobacterium Ti Plasmids
Chapter 18: The Influence of Biofilms in the Biology of Plasmids
Chapter 19: The Partitioning and Copy Number Control Systems of the Selfish Yeast Plasmid
Chapter 20: Plasmids from Euryarchaeota

V. Plasmid Ecology and Evolution
Chapter 21: The Plasmidome of Firmicutes: Impact on the Emergence and the Spread…
Chapter 22: Plasmid-Mediated Antimicrobial Resistance in Staphylococci and Other Firmicutes
Chapter 23: Plasmid Detection, Characterization, and Ecology
Chapter 24: Plasmid-Mediated Antibiotic Resistance and Virulence in Gram-Negatives…
Chapter 25: Plasmid-Mediated Quinolone Resistance

VI. Specialized Functions Mediated by Plasmids
Chapter 26: Plasmid-Mediated Tolerance Toward Environmental Pollutants
Chapter 27: Virulence Plasmids of Spore-Forming Bacteria
Chapter 28: Virulence Plasmids of Nonsporulating Gram-Positive Pathogens
Chapter 29: Plasmid-Encoded Iron Uptake Systems

VII. Plasmids as Genetic Tools
Chapter 30: DNA Assembly Tools and Strategies for the Generation of Plasmids
Chapter 31: Plasmids as Tools for Containment
Chapter 32: Mining Environmental Plasmids for Synthetic Biology Parts and Devices
Chapter 33: Using Plasmids as DNA Vaccines for Infectious Diseases
Chapter 34: Plasmid Biopharmaceuticals

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Tags: Marcelo Tolmasky, Juan Carlos Alonso, Plasmids, biotechnology