Topical and Transdermal Drug Delivery Principles and Practice 1st Edition by Heather Benson, Adam Watkinson 0470450290 978-0470450291

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Product details:

ISBN 10: 0470450290
ISBN 13: 978-0470450291
Author:  Heather A. E. Benson, Adam C. Watkinson

Practical drug development approaches presented by leading experts

Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products. Drawing together and reviewing the latest research findings, the book focuses on practical, tested, and proven approaches that are backed by industry case studies and the authors’ firsthand experience. Moreover, the book emphasizes the mechanistic information that is essential for successful drug product development.

Topical and Transdermal Drug Delivery Principles and Practice 1st Table of contents:

Part One: Current Science, Skin Permeation, and Enhancement Approaches

CHAPTER 1
Skin Structure, Function, and Permeation (Pages: 1-22)

CHAPTER 2
Passive Skin Permeation Enhancement (Pages: 23-42)

CHAPTER 3
Electrical and Physical Methods of Skin Penetration Enhancement (Pages: 43-65)

CHAPTER 4
Clinical Applications of Transdermal Iontophoresis (Pages: 67-83)

CHAPTER 5
In Vitro Skin Permeation Methodology (Pages: 85-108)

CHAPTER 6
Skin Permeation Assessment: Tape Stripping (Pages: 109-130)

CHAPTER 7
Skin Permeation Assessment: Microdialysis (Pages: 131-153)

CHAPTER 8
Skin Permeation: Spectroscopic Methods (Pages: 155-166)

CHAPTER 9
Skin Permeation Assessment in Man: In Vitro–In Vivo Correlation (Pages: 167-182)

CHAPTER 10
Risk Assessment (Pages: 183-199)

Part Two: Topical and Transdermal Product Development

CHAPTER 11
An Overview of Product Development from Concept to Approval (Pages: 201-215)

CHAPTER 12
Regulatory Aspects of Drug Development for Dermal Products (Pages: 217-232)

CHAPTER 13
Toxicological and Pre-Clinical Considerations for Novel Excipients and New Chemical Entities (Pages: 233-254)

CHAPTER 14
Topical Product Formulation Development (Pages: 255-286)

CHAPTER 15
Transdermal Product Formulation Development (Pages: 287-308)

CHAPTER 16
Sensitivity and Irritation Testing (Pages: 309-343)

CHAPTER 17
New Product Development for Transdermal Drug Delivery: Understanding the Market Opportunity (Pages: 345-355)

CHAPTER 18
Transdermal and Topical Drug Delivery Today (Pages: 357-366)

CHAPTER 19
Current and Future Trends: Skin Diseases and Treatment (Pages: 367-407)

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Heather Benson,Adam Watkinson,Transdermal Drug Delivery Principles