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Antisense Therapeutics 2nd Edition by Ian Phillips 9781592598540 1592598544

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Antisense Therapeutics 2nd Ed Edition Wafik S. El-Deiry Digital Instant Download

Author(s): Wafik S. El-Deiry
ISBN(s): 9781592598540, 1592598544
Edition: 2nd Ed
File Details: PDF, 5.62 MB
Year: 2004
Language: english
SKU: EB-1291044 Category: Tag:

Antisense Therapeutics 2nd Edition by Ian Phillips – Ebook PDF Instant Download/Delivery: 9781592598540, 1592598544

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Product details:

ISBN 10: 1592598544

ISBN 13: 9781592598540

Author: M. Ian Phillips

A timely primer on the new reality of antisense and RNA inhibition for treating a broad range of diseases. The authors show how antisense oligonucleotides are being designed and studied in relation to hypertension, various cancers, inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery. Highlights include RNA-based therapies for many diseases, up-to-date methods and applications, and insight into the enormous potential to provide a new generation of drugs.

Table of contents:

  1. Antisense Therapeutics

  2. Antisense Inhibition

  3. Cardiovascular

  4. Local Application of Antisense for Prevention of Restenosis

  5. Antisense Therapeutics for Hypertension

  6. Antisense Strategies for the Treatment of Heart Failure

  7. Cancer

  8. Clinical Studies of Antisense Oligonucleotides for Cancer Therapy

  9. Antisense Therapy in Clinical Oncology

  10. Radionuclide-Peptide Nucleic Acid in Diagnosis and Treatment of Pancreatic Cancer

  11. Suppression of Pancreatic and Colon Cancer Cells by Antisense K-ras RNA Expression Vectors

  12. Induction of Tumor Cell Apoptosis and Chemosensitization by Antisense Strategies

  13. Utility of Antioncogene Ribozymes and Antisense Oligonucleotides in Reversing Drug Resistance

  14. Blood—Brain Barrier

  15. Transport of Antisense Across the Blood-Brain Barrier

  16. Dermal

  17. Transdermal Delivery of Antisense Oligonucleotides

  18. Drugs

  19. Antisense Strategies for Redirection of Drug Metabolism

  20. Gastrointestinal

  21. Antisense Oligonucleotide Treatment of Inflammatory Bowel Diseases

  22. Hepatitis

  23. Optimizing Electroporation Conditions for Intracellular Delivery of Morpholino Antisense Oligonucleotides Directed Against the Hepatitis C Virus Internal Ribosome Entry Site

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Tags: Ian Phillips, Antisense, Therapeutics