The Pulmonary Epithelium in Health and Disease 1st Edition by David Proud ISBN 0470059516 9780470059517

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ISBN 10: 0470059516 
ISBN 13: 9780470059517
Author: David Proud

“This is essential reading for everyone who would like to update their knowledge of the pulmonary epithelium.  It offers a comparison between laboratory animal models and human lungs, highlighting the differences and the similarities between the two, which will be particularly useful to researchers.” –Doody’s, April 2009

The past two decades have seen extraordinary advances in our understanding of the role of the pulmonary epithelium in airway health and disease. Our understanding of epithelial biology has expanded exponentially in the past decade.

This book provides a unique comprehensive description of the structure of the epithelium, its damage by various agents and the mechanism of epithelial repair. In addition, it’s detailed coverage includes not only the multiple ways in which the epithelium contributes to host defence, but also the nature and functional consequences of the interactions of inhaled pathogens, including viruses, bacteria, allergens and pollutants. the role of the epithelium in regulating airway inflammation and structure is also discussed, as is the role of the epithelium as a target for inhaled medications and as a route for novel drug delivery.

Containing chapters on multiple aspects of epithelial function in health and disease, each one is written by a leader in the field. This is essential reading for pulmonary researchers and physicians requiring detailed advanced understanding of the epithelium as well as those working in allergy, biomedical and pharmaceutical research.

The Pulmonary Epithelium in Health and Disease 1st Table of contents:

• Chapter 1: Pulmonary Epithelium: Cell Types and Functions

  • Mary Mann-Jong Chang, Laura Shih and Reen Wu

• Chapter 2: Epithelial Adhesive Structures and Adhesion Molecule Expression

  • George Su and Dean Sheppard

• Chapter 3: The Epithelium as a Target

  • Louise E. Donnelly

• Chapter 4: Epithelial Repair and Function

  • Carl G. A. Persson, Morgan Andersson and Lena Uller

• Chapter 5: Integration of Epithelial Ion Transport Activities into Airway Surface Liquid Volume and Ion Composition Regulation

  • Mark T. Clunes, Peter F. Bove and Richard C. Boucher

• Chapter 6: Structure and Function of Cilia

  • Andreas Schmid and Matthias Salathe

• Chapter 7: Composition and Function of Airway Mucus

  • Duncan F. Rogers

• Chapter 8: The Pulmonary Surfactant System

  • Nicole A. Rocca, Ruud A.W. Veldhuizen and James F. Lewis

• Chapter 9: Microbial Recognition by Epithelium

  • Catherine M. Greene and Stephen G. J. Smith

• Chapter 10: Epithelial Antimicrobial Molecules

  • Pieter S. Hiemstra

• Chapter 11: The Epithelium and Immunoregulation

  • Angela Rate and John W. Upham

• Chapter 12: Interactions of Respiratory Viruses with the Epithelium

  • Umadevi S. Sajjan, Dawn C. Newcomb, Toby C. Lewis, Christine S. Stahle and Marc B. Hershenson

• Chapter 13: Bacterial Interactions with the Airway Epithelium

  • Marisa I. Gómez and Alice Prince

• Chapter 14: Interactions of Pollutants with the Epithelium

  • Ernst Wm. Spannhake

• Chapter 15: Interactions between Allergens and the Airway Epithelium

  • Clive Robinson, Jihui Zhang, Geoffrey A. Stewart

• Chapter 16: The Epithelium as a Regulator of Airway Inflammation

  • Richard Leigh and David Proud

• Chapter 17: The Epithelium and Airway Remodelling

  • Stephen T. Holgate

• Chapter 18: Modulation of Epithelial Cell Function by Glucocorticoids: Anti-inflammatory and Other Effects

  • Robert Newton, Manminder Kaur, Elizabeth M. King, Wei Gong, Donna M. Slater and Neil S. Holden

• Chapter 19: The Airway Epithelium as a Target for the Therapeutic Actions of β2​-Adrenoceptor Agonists and Muscarinic-receptor Antagonists

  • Mark A. Giembycz

• Chapter 20: Pulmonary Delivery of Novel Therapies

  • Bruce Rubin and James B. Fink

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Tags: David Proud, Pulmonary, Epithelium