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Bioinformatics Volume II Structure Function and Applications 1st Edition by Jonathan Keith 9781603274289 1603274286

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Bioinformatics Structure Function and Applications 1st Edition Nicholas R. Markham Digital Instant Download

Author(s): Nicholas R. Markham, Michael Zuker (auth.), Jonathan M. Keith PhD (eds.)
ISBN(s): 9781603274289, 1603274286
Edition: 1
File Details: PDF, 9.37 MB
Year: 2008
Language: english
SKU: EB-1079628 Category: Tags: , ,

Bioinformatics Volume II Structure Function and Applications 1st Edition by Jonathan Keith – Ebook PDF Instant Download/Delivery: 9781603274289, 1603274286

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Product details:

ISBN 10: 1603274286

ISBN 13: 9781603274289

Author: Jonathan M. Keith

Not only is the quantity of life science data expanding, but new types of biological data continue to be introduced as a result of technological development and a growing understanding of biological systems. Methods for analyzing these data are an increasingly important component of modern biological research. In Bioinformatics, leading researchers in the field provide a selection of the most useful and widely applicable methods, able to be applied as is, or with minor variations, to many specific problems. Volume II: Structure, Function and Applications contains methods pertinent to the prediction of protein and RNA structures and the analysis and classification of structures, methods for inferring the function of previously identified genomic elements, chiefly protein-coding genes, medical applications in diagnostics and drug discovery, and “meta-methods” for developers of bioinformatics algorithms.

Table of contents:

Chapter 1. Structures – UNAFold

Chapter 2. Protein Structure Prediction

Chapter 3. An Introduction to Protein Contact Prediction

Chapter 4. Analysis of Mass Spectrometry Data in Proteomics

Chapter 5. The Classification of Protein Domains

Chapter 6. Inferring Function from Homology

Chapter 7. The Rosetta Stone Method

Chapter 8. Inferring Functional Relationships from Conservation of Gene Order

Chapter 9. Phylogenetic Profiling

Chapter 10. Phylogenetic Shadowing

Chapter 11. Prediction of Regulatory Elements

Chapter 12. Expression and Microarrays

Chapter 13. Identifying Components of Complexes

Chapter 14. Integrating Functional Genomics Data

Chapter 15. Computational Diagnostics with Gene Expression Profiles

Chapter 16. Analysis of Quantitative Trait Loci

Chapter 17. Molecular Similarity Concepts and Search Calculations

Chapter 18. Optimization of the MAD Algorithm for Virtual Screening

Chapter 19. Combinatorial Optimization Models for Finding Genetic Signatures from Gene Expression Datasets

Chapter 20. Genetic Signatures for a Rodent Model of Parkinson’s Disease Using Combinatorial Optimization Methods

Chapter 21. Developing Fixed-Parameter Algorithms to Solve Combinatorially Explosive Biological Problems

Chapter 22. Clustering

Chapter 23. Visualization

Chapter 24. Constructing Computational Pipelines

Chapter 25. Text Mining

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Tags: Jonathan Keith, Bioinformatics, Structure, Function