Burger’s Medicinal Chemistry and Drug Discovery Vol 2 Drug Discovery and Drug Development 6th Edition by Donald Abraham 0471370282 9780471370284

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Product details:

ISBN 10: 0471370282 

ISBN 13: 9780471370284

Author: Donald J. Abraham

This is Volume 2: Drug Discovery and Drug Development, of Burger’s Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Combinational Chemistry and Multiple Parallel Synthesis, High Throughput Pharmacology, and Retrometabolism-Based Drug Design and Targeting.

Table of contents:

1. Combinatorial Chemistry and Multiple Parallel Synthesis

2. High-Throughput Screening for Lead Discovery

3. High-Throughput Pharmacology

4. Application of Recombinant DNA Technology in Medicinal Chemistry and Drug Discovery

5. Oligonucleotide Therapeutics

6. Therapeutic Agents Acting on RNA Targets

7. Carbohydrate-Based Therapeutics

8. Membrane Transport Proteins and Drug Transport

9. Allosteric Proteins and Drug Discovery

10. Receptor Targets in Drug Discovery and Development

11. Nicotinic Acetylcholine Receptors

12. Large-Scale Synthesis

13. Principles of Drug Metabolism

14. Metabolic Considerations in Prodrug Design

15. Retrometabolism-Based Drug Design and Targeting

16. Drug Discovery: The Role of Toxicology

17. Drug Absorption, Distribution, and Elimination

18. Physicochemical Characterization and Principles of Oral Dosage Form Selection

19. The FDA and Regulatory Issues

20. Intellectual Property in Drug Discovery and Biotechnology

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Tags: Donald Abraham, Medicinal, Chemistry, Discovery