Chapter 1. Identification and Quantification of Histone PTMs using High-Resolution Mass Spectrometry
Chapter 2. Substrate Specificity Profiling of Histone-Modifying Enzymes by Peptide Microarray
Chapter 3. ArrayNinja: An Open Source Platform for Unified Planning and Analysis of Microarray Experiments
Chapter 4. Chemical Biology Approaches for Characterization of Epigenetic Regulators
Chapter 5. Mapping Lysine Acetyltransferase-Ligand Interactions by Activity-Based Capture
Chapter 6. Investigating Histone Acetylation Stoichiometry and Turnover Rate
Chapter 7. Rapid Semisynthesis of Acetylated and Sumoylated Histone Analogs
Chapter 8. An IF-FISH Approach for Co-Visualization of Gene Loci and Nuclear Architecture in Fission Yeast
Chapter 9. Biology, Chemistry and Pharmacology of Sirtuins
Chapter 10. Synthesis and Assay of SIRT1 Activating Compounds
Chapter 11. Synthesis and Assays of Inhibitors of Methyltransferases
Chapter 12. Exploring the Dynamic Relationship between Cellular Metabolism and Chromatin Structure using SILAC-Mass Spec and ChIP-Sequencing
Chapter 13. Current Proteomic Methods to Investigate the Dynamics of Histone Turnover in the Central Nervous System
Chapter 14. ChIP-Sequencing to Map the Epigenome of Senescent Cells using Benzonase Endonuclease
Chapter 15. Exploiting Chromatin Biology to Understand Immunology