Constitutive Activity in Receptors and Other Proteins Part 2 1st Edition by Melvin Simon ISBN 978-0123812995 0123812995

Constitutive Activity in Receptors and Other Proteins Part 2 1st Edition by Melvin I. Simon- Ebook PDF Instant Download/Delivery: 978-0123812995,  0123812995 
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Product details: 

ISBN 10:  0123812995 

ISBN 13:  978-0123812995

Author: Melvin I. Simon

This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins. The chapters written by expert authors who are leaders in the field, provide hints and tricks not available in primary research publications.It is extensively referenced, with useful figures and tables throughout the volume.

– Expert authors who are leaders in the field
– Extensively referenced and useful figures and tables
– Provides hints and tricks to facilitate reproduction of methods

Table of contents: 

1. Constitutive Activity at the Cannabinoid CB1 Receptor and Behavioral Responses

2. Detecting Constitutive Activity and Protean Agonism at the Cannabinoid CB2 Receptor

3. Modulation of Constitutive Activity of the Ghrelin Receptor by Pharmacological Tools and Mutagenesis

4. Assessment of Constitutive Activity and Internalization of GPR54 (Kiss1-r)

5. Assessment of Constitutive Activity in EP Prostanoid Receptors

6. α1D-Adrenergic Receptors: Constitutive Activity and Reduced Expression at the Plasma Membrane

7. Constitutive Activity of the Histamine H1 Receptor

8. Constitutive Activity of Somatostatin Receptor Subtypes

9. Assessment of Homologous Internalization of a Constitutively Active AT1 Receptor Mutant

10. Methods to Detect Cell Surface Expression and Constitutive Activity of GPR6

11. β3-Adrenoceptor Agonists and Inverse Agonists: Constitutive Activity and Stereospecific Binding

12. Constitutive Activity of the Lutropin Receptor and Its Allosteric Modulation

13. Assessing Constitutive Activity of Extracellular Calcium-Sensing Receptors

14. Constitutive Activity of Neural Melanocortin Receptors

15. Measurement of Constitutive Activity of BMP Type I Receptors

16. Constitutive Activity of Dopamine D1 and D5 Receptors and Their Mutants

17. Identification of Gain-of-Function Variants of the Human Prolactin Receptor

18. Activated ACVR1/ALK2 and Constitutive Signaling in Fibrodysplasia Ossificans Progressiva

19. Constitutively Active Thyroid-Stimulating Hormone Receptor Mutations

20. Assessment of Constitutive Activity of the GPCR Cpr2 in Cryptococcus neoformans

21. In Vitro and In Vivo Assessment of Mu Opioid Receptor Constitutive Activity

22. Constitutively Active μ-Opioid Receptor: Methods

23. Protein Kinase CK2 as a Constitutively Active Enzyme Promoting Cell Survival

24. Assessment of CK2 Constitutive Activity in Cancer Cells

25. Structural Basis of the Constitutive Activity of Protein Kinase CK2

26. Measuring Constitutive Activation of c-Jun N-Terminal Kinase Isoforms

27. Measurement of Constitutive MAPK and PI3K/AKT Signaling Activity

28. Constitutive Activity of GPR40/FFA1

29. Constitutive Activity of TRP Channels

30. Measurement of Orexin and Substance P Effects on Constitutively Active Kir Channels

31. Characterization of G Protein Receptor Kinase 4 Constitutive Activity In Vivo

32. Voltage-Clamp Methods for Detecting Constitutively Active Acetylcholine-Gated IK,ACh Channels

33. Assaying Constitutive Activity of the WAVE and WASH Complexes Toward Arp2/3

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Tags: Melvin Simon, Constitutive Activity, Other Proteins