Essential Developmental Biology 2nd Edition by Jonathan Slack 1405122161 9781405122160

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ISBN 10: 1405122161 

ISBN 13: 9781405122160

Author: Jonathan M. W. Slack

TO ACCESS THE DEDICATED TEXTBOOK WEBSITE, PLEASE VISIT www.blackwellpublishing.com/slack Essential Developmental Biology, 2nd Edition, is a concise and well-illustrated treatment of this subject for undergraduates. With an emphasis throughout on the evidence underpinning the main conclusions, this book is suitable as the key text for both introductory and more advanced courses in developmental biology. Includes new chapters on Evolution & Development, Gut Development, & Growth and Aging. Contains expanded treatment of mammalian fertilization, the heart and stem cells. Now features a glossary, notated further reading, and key discovery boxes. Illustrated with over 250 detailed, full-color drawings. Accompanied by a dedicated website, featuring animated developmental processes, a photo gallery of selected model organisms, and all art in PowerPoint and jpeg formats (also available to instructors on CD-ROM). An Instructor manual CD-ROM for this title is available. Please contact our Higher Education team at HigherEducation@wiley.com for more information.

Table of contents:

Section 1: Groundwork
Chapter 1 The excitement of developmental biology
Where the subject came from
Central position in biology
Impact on society
Future impact

Chapter 2 Common features of development
Genomic equivalence, cloning of animals
Gametogenesis
Early development
Morphogenetic processes
Growth and death

Chapter 3 Developmental genetics
Developmental mutants
Screening for mutants
Cloning of genes
Transgenesis
Gene duplication

Chapter 4 Experimental embryology
Normal development
Developmental commitment
Acquisition of commitment
Homeotic genes
Criteria for proof

Chapter 5 Techniques for the study of development
Microscopy
Study of gene expression by biochemical methods
Study of gene expression by in situ methods
Reporter genes
Microinjection
Cell-labeling methods
Cell sorting

Section 2: Major model organisms
Chapter 6 Model organisms
The big six
Availability and cost
Access and micromanipulation
Genetics and genome maps
Relevance and tempo

Chapter 7 Xenopus
Oogenesis, maturation, fertilization
Embryonic development
Experimental methods
Regional specification
Inductive interactions

Chapter 8 The zebrafish
Normal development
Mutagenesis
Regional specification

Chapter 9 The chick
Normal development
Regional specification of the early embryo
Description of organogenesis in the chick

Chapter 10 The mouse
Mammalian fertilization
Normal embryonic development
Technology of mouse development
Regional specification in development
Other topics in mouse development

Chapter 11 Drosophila
Insects
Normal development
Drosophila developmental genetics
Overview of the developmental program
The dorsoventral pattern
The anteroposterior system

Chapter 12 Caenorhabditis elegans
Normal development
Regional specification in the embryo
Analysis of postembryonic development
Programmed cell death

Section 3: Organogenesis
Chapter 13 Tissue organization and stem cells
Types of tissue
Tissue renewal
Skin
Intestine
Hematopoietic system

Chapter 14 Development of the nervous system
Overall structure and cell types
Anteroposterior patterning of the neural plate
Dorsoventral patterning of the neural tube
Neurogenesis and gliogenesis
The neural crest
Development of neuronal connectivity

Chapter 15 Development of mesodermal organs
Somitogenesis and myogenesis
The kidney
Germ cell and gonadal development
Limb development
Heart and blood vessels

Chapter 16 Development of endodermal organs
Normal development
Determination of the endoderm
The pancreas

Chapter 17 Drosophila imaginal discs
Metamorphosis
Genetic study of larval development
Mitotic recombination
Disc development
Regional patterning of the wing disc

Section 4: Growth, regeneration, and evolution
Chapter 18 Growth, aging, and cancer
Size and proportion
Growth in stature
Aging
Postnatal disorders of growth and differentiation

Chapter 19 Regeneration of missing parts
Planarian regeneration
Vertebrate limb regeneration

Chapter 20 Evolution and development
Macroevolution
The primordial animal
What really happened in evolution?

Appendix: Key molecular components
Genes
Transcription factor families
Signaling systems
Inducing factor families
Cytoskeleton
Cell adhesion molecules
Extracellular matrix components

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