Introduction to Ecological Genomics 2nd Edition by Nico van Straalen, Dick Roelofs 0199594686 9780199594689

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ISBN 10: 0199594686

ISBN 13: 9780199594689

Author: Nico M. van Straalen, Dick Roelofs

The genomics revolution has expanded from its origins in molecular biology to impact upon every discipline in the life sciences, including ecology. Several lines of ecological research can now be profitably addressed using genomics technology, including issues of nutrient cycling, population structure, life-history variation, trophic interaction, stress responses, and adaptation to environmental change. This new edition addresses a series of fundamental ecological questions: the relationship between community structure and ecological function in ecosystems; how variation in life-history patterns among species can be explained from interaction between the genome and the environment; the molecular responses to changing and toxic environmental conditions; adaptive phenotypes and their relationship to genetic variation. Each of these questions is evaluated in the light of recent advances in genomics research, paying particular attention to data obtained from sequencing and screening of environmental genomes (metagenomics), microarray-based transcription profiling, gene expression directed by signal-transduction pathways, and the analysis of genomic polymorphisms. The chapters covering these key areas are preceded by discussions of genomics methodology (including an overview of next-generation sequencing technologies) and comparative genomics, and the book concludes with a chapter on integrative approaches such as ecological control analysis. The authors also provide a comparative survey of the properties of genomes (genome size, gene families, synteny, and polymorphism) for prokaryotes as well as the main eukaryotic models. An Introduction to Ecological Genomics incorporates a balance of plant, animal, and microbial examples, and continues to define the new and exciting field of ecological genomics.

Introduction to Ecological Genomics 2nd Table of contents:

1 Ecological genomics and genome analysis

1.1 The genomics revolution invading ecology

1.2 Yeast, fly, worm, and weed

1.3 -Omics speak

1.4 Genome analysis

2 Comparing genomes

2.1 Properties of genomes

2.2 Prokaryotic genomes

2.3 Eukaryotic genomes

3 Structure and function in communities

3.1 The biodiversity and ecosystem functioning synthetic framework

3.2 Measurement of microbial biodiversity

3.3 Microbial genomics of biogeochemical cycles

3.4 Reconstruction of functions from environmental genomes

3.5 Genomic approaches to biodiversity and ecosystem function: an appraisal

4 Life-history patterns

4.1 The core of life-history theory

4.2 Longevity and aging

4.3 Gene-expression profiles in the life cycle

4.4 Phenotypic plasticity of life-history traits

4.5 Genomic approaches to life-history patterns: an appraisal

5 Stress responses

5.1 Stress and the ecological niche

5.2 The main defence mechanisms against cellular stress

5.3 Heat, cold, drought, salt, and hypoxia

5.4 Herbivory and microbial infection

5.5 Toxic substances

5.6 Genomic approaches to ecological stress: an appraisal

6 Variation and adaptation

6.1 The internal tangled bank

6.2 Genomic polymorphisms

6.3 Regulatory and structural change

6.4 Epigenetic variation and developmental change

6.5 Genomic approaches to variation and adaption: an appraisal

7 Integrative ecological genomics

7.1 The need for integration: systems biology

7.2 Ecological control analysis

7.3 Outlook

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Nico van Straalen,Dick Roelofs,Introduction,Ecological