A Guide to Zona Pellucida Domain Proteins 1st Edition by Eveline Litscher, Paul Wassarman 0470528117 9780470528112

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ISBN 10: 0470528117

ISBN 13: 9780470528112

Author: Eveline S. Litscher, Paul M. Wassarman

This book provides a coherent, clear, and uniform presentation of structural, genetic, molecular, and biochemical information available for the zona pellucida domain protein family, which impact pathologies such as infertility, deafness, and cancer. Furthermore it: Details information about the structure and function of the ZP domain in ZPDC-proteins Provides illustrations of the organization of ZPDC-proteins, the genes that encode the proteins, and examples of mutations in the ZP domain that cause diseases Speculates as to the evolution of the ZP domain and potential therapeutics for diseases stemming from ZP domain mutations Addresses mammalian and non-mammalian systems

A Guide to Zona Pellucida Domain Proteins 1st Table of contents:

PART A: ZONA PELLUCIDA DOMAIN PROTEINS
A.1 NATURE OF THE ZONA PELLUCIDA DOMAIN
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A.2 MOUSE ZP PROTEINS
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A.3 SYNTHESIS, SECRETION, AND ASSEMBLY OF ZP PROTEINS
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A.4 STRUCTURE OF THE ZPD
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A.5 EVOLUTION OF ZPD PROTEINS
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PART B: MAMMALIAN ZONA PELLUCIDA PROTEINS
B.1 INTRODUCTION
B.2 MONOTREMES
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B.3 MARSUPIALS
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B.4 PLACENTAL MAMMALS
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B.5 MAMMALIAN ZP PROTEINS AS ANTIFERTILITY VACCINES
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B.6 SUMMARY TABLES

PART C: MAMMALIAN ZONA PELLUCIDA DOMAIN PROTEINS
C.1 BETAGLYCAN/TGFβ-RECEPTOR TYPE III
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C.2 CUB AND ZONA PELLUCIDA-LIKE DOMAIN 1 (CUZD-1) PROTEINS
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C.3 DELETED IN MALIGNANT BRAIN TUMOR 1 (DMBT1) PROTEINS
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C.4 ENDOGLIN/CD-105
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C.5 LIVER-SPECIFIC ZPD-CONTAINING PROTEIN (LZP)
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C.6 OOCYTE-SECRETED PROTEIN 1 (Oosp1)
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C.7 PANCREATIC ZYMOGEN GRANULE PROTEIN (GP-2)
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C.8 PLACENTA-SPECIFIC 1 (PLAC1)
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C.9 TECTORIN-α AND -β
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C.10 UROMODULIN/TAMM–HORSFALL PROTEIN
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C.11 UROMODULIN-LIKE PROTEINS
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C.12 SUMMARY TABLES

PART D: NON-MAMMALIAN ZONA PELLUCIDA DOMAIN PROTEINS
D.1 JELLYFISH (AURELIA AURITA)
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D.2 SEA URCHINS (STRONGYLOCENTROTUS PURPURATUS)
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D.3 NEMATODES (CAENORHABDITIS ELEGANS)
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D.4 MOLLUSKS (HALIOTIS RUFESCENS)
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D.5 FRUIT FLIES (DROSOPHILA MELANOGASTER)
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D.6 TUNICATES: VITELLINE COAT PROTEINS AND OIKOSINS
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D.7 FISH: VITELLINE ENVELOPE PROTEINS
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D.8 AMPHIBIANS: VITELLINE ENVELOPE PROTEINS
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D.9 REPTILES: PREDICTED ZPD PROTEINS
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D.10 BIRDS: VITELLINE ENVELOPE PROTEINS
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D.11 SUMMARY TABLES

PART E: APPENDIX
APPENDIX: TABLE E.1
APPENDIX: TABLE E.2
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APPENDIX: TABLE E.3
APPENDIX: TABLE E.4
APPENDIX: TABLES E.5A AND E.5B

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Tags: Eveline Litscher, Paul Wassarman, Pellucida, Domain