Antimicrobial pharmacodynamics in theory and clinical practice 2nd Edition by Charles Nightingale, Paul Ambrose, George Drusano, Takeo Murakawa 0824729250 9780824729257

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Product details:

ISBN 10: 0824729250

ISBN 13: 9780824729257

Author: Charles H. Nightingale; Paul G. Ambrose; George L. Drusano; Takeo Murakawa

Taking readers from the research laboratory to the bedside, this Second Edition compiles essential information on the pharmacodynamics of all major classes of the antimicrobial armamentarium including penicillins, cephalosposorins, cephamycins, carbapenems, monobactams, aminoglycosides, quinolones, macrolides, antifungals, antivirals, and emerging

Antimicrobial pharmacodynamics in theory and clinical practice 2nd Table of contents:

Section I: Introduction
1 Pharmacodynamics of Antimicrobials: General Concepts and Applications
2 Applying Pharmacodynamics for Susceptibility Breakpoint Selection and Susceptibility Testing

Section II: Non-clinical Models of Infection
3 In Vitro Dynamic Models as Tools to Predict Antibiotic Pharmacodynamics
4 Animal Models of Infection for the Study of Antibiotic Pharmacodynamics
5 The Predictive Value of Laboratory Tests for Efficacy of Antibiotic Combination Therapy

Section III: Antibacterial Agents
6 b-Lactam Pharmacodynamics
7 Aminoglycosides
8 Quinolones
9 Glycopeptide Pharmacodynamics
10 Macrolide, Azalide, and Ketolides
11 Metronidazole and Clindamycin for Anaerobic Infections
12 Streptogramins and Oxazolidinones
13 Pharmacokinetics and Pharmacodynamics of Tetracyclines

Section IV: Antiviral Agents
14 The Clinical Pharmacology of Nucleoside Reverse Transcriptase Inhibitors
15 Pharmacodynamics of Antivirals

Section V: Antifungal Agents
16 Antifungal Agents Pharmacokinetics and Pharmacodynamics of Amphotericin B
17 Pharmacokinetics and Pharmacodynamics of Azoles
18 Glucan Synthase Inhibitors

Section VI: Antimalarial Agents
19 Antimalarial Agents

Section VII: Pharmacodynamics in Drug Development
20 Human Pharmacodynamics of Anti-infectives: Determination from Clinical Trial Data
21 Application of Pharmacokinetics and Pharmacodynamics in Antimicrobial Global Drug Development
22 Modeling of Toxicities Due to Antibiotics

Section VIII: Pharmacodynamics and Resistance
23 Pharmacodynamics and Antibacterial Resistance

Section IX: Application of PK-PD to Clinical and Formulary Decisions
24 The Principles of Pharmacoeconomics

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Tags: Charles Nightingale, Paul Ambrose, George Drusano, Antimicrobial