Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats 1st Edition by Paul Torrence – Ebook PDF Instant Download/Delivery: 0471668273, 9780471668275
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Product details:
ISBN 10: 0471668273
ISBN 13: 9780471668275
Author: Paul F. Torrence
Antiviral Drug Discovery gives readers a cutting-edge view of how chemical concepts are being mobilized to develop novel approaches that will effectively confront emerging diseases and biowarfare. Among the many topics discussed are smallpox, the Ebola virus, influenza, SARS, arenaviruses and flaviviruses. Each chapter discusses hypothetical strategies for the discovery of relevant antiviral agents, recent findings related to biochemistry or drug discovery, and advances in the further development of established leads in the area. Timely and informative, this book clearly delineates the efforts being made to develop new and effective broad-spectrum antiviral agents.
Table of contents:
CHAPTER 1: Introduction: Pestilence, Plague, Bioterrorism
CHAPTER 2: Viral Bioterrorism and Antiviral Countermeasures
CHAPTER 3: Overview of Antiviral Drug Discovery and Development
CHAPTER 4: Antiviral Drug Targets and Strategies for Emerging Viral Diseases and Bioterrorism Threats
CHAPTER 5: Perspectives for the Therapy against Arenavirus Infections
CHAPTER 6: S-Adenosylhomocysteine Hydrolase Inhibitors As a Source of Anti-Filovirus Agents
CHAPTER 7: Antiviral Strategies for Ebola Virus
CHAPTER 8: IMPDH Inhibitors: Discovery of Antiviral Agents against Emerging Diseases
CHAPTER 9: Lethal Mutagenesis: Exploiting Error-Prone Replication of Riboviruses for Antiviral Therapy
CHAPTER 10: Structural Biology of Flaviviral Replication and Opportunities for Drug Design
CHAPTER 11: Confronting New and Old Antiviral Threats: Broad Spectrum Potential of Prenylation Inhibitors
CHAPTER 12: West Nile Virus: New Targets for Potential Antivirals
CHAPTER 13: The Emergence of Pandemic Influenza A: Bioterrorist Versus Mother Nature
CHAPTER 14: Discovery and Development of New Antivirals for Smallpox
CHAPTER 15: Viral Countermeasures to the Host Interferon Response: Role of the Vaccinia Virus E3L and K3L Genes
CHAPTER 16: Broad-Spectrum Antiviral Prophylaxis: Inhibition of Viral Infection by Polymer Grafting with Methoxypoly(Ethylene Glycol)
CHAPTER 17: Viral Evasion of the Interferon System: Novel Targets for Drug Discovery
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Tags: Paul Torrence, Antiviral, Discovery, Emerging