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Attrition in the pharmaceutical industry reasons implications and pathways forward 1st Edition by Alexander Alex, John Harris, Dennis Smith 9781118679678 1118679679

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Attrition in the pharmaceutical industry reasons implications and pathways forward 1st Edition Alex Digital Instant Download

Author(s): Alex, Alexander A.; Harris, C. John; Smith, Dennis A
ISBN(s): 9781118679678, 1118679679
Edition: 1
File Details: PDF, 5.69 MB
Year: 2015
Language: english
SKU: EB-5300854 Category: Tags: , , , , ,

Attrition in the pharmaceutical industry reasons implications and pathways forward 1st Edition by Alexander Alex, John Harris, Dennis Smith – Ebook PDF Instant Download/Delivery: 9781118679678, 1118679679

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Product details:

ISBN 10: 1118679679

ISBN 13: 9781118679678

Author: Alexander Alex; C. John Harris; Dennis A. Smith

With a focus on case studies of R&D programs in a variety of disease areas, the book highlights fundamental productivity issues the pharmaceutical industry has been facing and explores potential ways of improving research effectiveness and efficiency. • Takes a comprehensive and holistic approach to the problems and potential solutions to drug compound attrition • Tackles a problem that adds billions of dollars to drug development programs and health care costs • Guides discovery and development scientists through R&D stages, teaching requirements and reasons why drugs can fail • Discusses potential ways forward utilizing new approaches and opportunities to reduce attrition

Table of contents:

  1. Attrition in Drug Discovery and Development

  2. Compound Attrition at the Preclinical Phase

  3. Attrition in Phase I

  4. Compound Attrition in Phase II/III

  5. Postmarketing Attrition

  6. Influence of the Regulatory Environment on Attrition

  7. Experimental Screening Strategies to Reduce Attrition Risk

  8. Medicinal Chemistry Strategies to Prevent Compound Attrition

  9. Influence of Phenotypic and Target-Based Screening Strategies on Compound Attrition and Project Choice

  10. In Silico Approaches to Address Compound Attrition

  11. Current and Future Strategies for Improving Drug Discovery Efficiency

  12. Impact of Investment Strategies, Organizational Structure and Corporate Environment on Attrition, and Future Investment Strategies to Reduce Attrition

 
 

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Tags: Alexander Alex, John Harris, Dennis Smith, Attrition