Chemical biology in regenerative medicine bridging stem cells and future therapies 1st Edition by Charles Hong, Ada Ao, Jijun Hao 1118349598 9781118349595

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Product details:

ISBN 10: 1118349598 

ISBN 13: 9781118349595

Author: Charles C. Hong, Ada S. Ao, Jijun Hao

Chemical Biology in Regenerative Medicine: Bridging Stem Cells and Future Therapies The field of regenerative medicine has advanced at a rapid pace and this comprehensive summary of new developments is a timely contribution to the field as clinical trials have begun to assess the safety and efficacy of cell-based therapies. In Chemical Biology in Regenerative Medicine, an international team of experts provides an overview of progress towards clinical application in the areas of transplantation (allogenic and autologous), manipulation of niche environment and homing, and cell reprogramming (trans-differentiation and de-differentiation). The book highlights the interdisciplinary approaches undertaken to resolve current technical problems in regenerative medicine, with special attention paid to small molecules and biomaterials engineering. This volume provides an essential overview of this emerging technology for researchers in academic, industrial and clinical environments working in regenerative medicine, chemical biology, biochemistry, cell biology, biomaterials and bioengineering. It is appropriate for training students and newcomers to the field, benefitting readers in broadening their knowledge and giving them insights to regenerative chemical biology, as well as encouraging readers to implement the key points in their own fields of study to develop new technologies.

Table of contents:

1. Wnt Signaling in Regulation of Stem Cells

2. Directed Cardiomyogenesis of Pluripotent Stem Cells

3. Chemical Genetics in Cardiomyocyte Generation

4. Challenges and New Directions for Cardiac Reprogramming

5. Comparative Analysis of Adult Stem Cell Niches

6. Chemicals and Stem Cells in the Promotion of Regeneration

7. Chemically Induced Pluripotent Stem Cells (CiPSCs): A Potential Chemical Biological Breakthrough in Reprogramming?

8. An Introduction to Cellular Reprogramming: The Plasticity of Cell Fates and Identities

9. Chemicals Facilitating Reprogramming

10. Chemicals Facilitating Reprogramming: Targeting the SAM Binding Site to Identify Novel Methyltransferase Inhibitors

11. Biomaterials for Directed Differentiation

12. Practicalities to Translation from the Clinic to the Market

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Tags: Charles Hong, Ada Ao, Jijun Hao, Chemical, regenerative