Design Principles for the Immune System and Other Distributed Autonomous Systems 1st Edition by Lee Segel, Irun Cohen 0198031343 9780198031345

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ISBN 10: 0198031343

ISBN 13: 9780198031345

Author: Lee A. Segel, Irun R. Cohen 

Design Principles for the Immune System and Other Distributed Autonomous Systems is the first book to examine the inner workings of such a variety of distributed autonomous systems–from insect colonies to high level computer programs to the immune system. It offers insight into the fascinating world of these systems that emerge from the interactions of seemingly autonomous components and brings us up-to-date on the state of research in these areas. Using the immune system and certain aspects of its functions as a primary model, this book examines many of the most interesting and troubling questions posed by complex systems. How do systems choose the right set of agents to perform appropriate actions with appropriate intensities at appropriate times? How in the immune system, ant colonies and metabolic networks does the diffusion and binding of a large variety of chemicals to their receptors permit coordination of system action? What advantages drive the various systems to complexity, and by what mechanisms do the systems cope with the tendency toward unwieldiness and randomness of large complex systems?

Design Principles for the Immune System and Other Distributed Autonomous Systems 1st Table of contents:

Part I: An Overview of Immunology

An Interpretative Introduction to the Immune System

Part II: Case Studies in Immune Complexity: Experiments

Cytokines: A Common Signaling System for Cell Growth, Inflammation, Immunity, and Differentiation

Th1/Th2 Effector Choice in the Immune System: A Developmental Program Influenced by Cytokine Signals

Oral Tolerance

Part III: Design Principles for the Immune System

An Introduction to Immuno-ecology and Immuno-informatics

The Creation of Immune Specificity

Diversity in the Immune System

T Cells Obey the Tenets of Signal Detection Theory

Diffuse Feedback from a Diffuse Informational Network: In the Immune System and Other Distributed Autonomous Systems

Multistep Navigation and the Combinatorial Control of Cell Positioning: A General Model for Generation of Living Structure Based on Studies of Immune Cell Trafficking

Distributed, Anarchic Immune Organization: Semi-autonomous Golems at Work

Part IV: Biochemical Systems

New Approaches to Complex Chemical Reaction Mechanisms

Part V: Social Insects

Control Mechanisms for Distributed Autonomous Systems: Insights from the Social Insects

Task Allocation in Ant Colonies

Part VI: Applications to Computer Science

Biologically Motivated Distributed Designs for Adaptive Knowledge Management

Analogy Making as a Complex Adaptive System

Immunology as Information Processing

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