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Drug DNA Interactions Structures and Spectra 1st Edition by Kazuo Nakamoto, Masamichi Tsuboi, Gary D Strahan ISBN 0471786268 9780471786269

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Drug DNA Interactions Structures and Spectra 1st Edition Kazuo Nakamoto Digital Instant Download

Author(s): Kazuo Nakamoto, Masamichi Tsuboi, Gary D. Strahan
ISBN(s): 9780471786269, 0471786268
Edition: 1
File Details: PDF, 17.25 MB
Year: 2008
Language: english
SKU: EB-1378260 Category: Tags: , ,

Drug DNA Interactions Structures and Spectra 1st Edition by Kazuo Nakamoto,  Masamichi Tsuboi, Gary D Strahan – Ebook PDF Instant Download/Delivery:0471786268, 9780471786269
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Product details: 

ISBN 10: 0471786268 

ISBN 13: 9780471786269

Author: Kazuo Nakamoto,  Masamichi Tsuboi, Gary D. Strahan 

Learn vital information about drug-DNA interactions from Drug-DNA Interactions: Structures and Spectra, the only comprehensive book written about this topic. Understand the types of structural and bonding information that can be obtained using specific physico-chemical methods and discover how to design new drugs that are more effective than current treatments and have fewer side effects. Find detailed information about X-ray crystallography, NMR spectroscopy, molecular modeling, and optical spectroscopy such as UV-Visible absorption, fluorescence, circular dichroism (CD), flow linear dichroism (FLD), infrared (IR) and Raman spectroscopy.

Table of contents: 

1. DNA Structures and Spectra.

1.1. DNA Structures.

1.2. Electronic Spectra.

1.3. Vibrational Spectra.

1.4. NMR Spectra.

1.5. Electron Spin Resonance Spectra.

1.6. X-Ray Crystallography.

1.7. Molecular Modeling an molecular Mechanics.

2. Intercalating Drugs.

2.1. Acridine Dyes.

2.2. Ethidium Bromide.

2.3. Aclacinomycin.

2.4. Sequence Preference.

2.5. Bis- and Tris- Intercalators.

3. Groove- Binding Drugs.

3.1. Netropsin and Distamycin.

3.2. Derivatives of Netropsin and Distamycin.

3.3. Hoechst 33258, SN6999, and their Derivatives.

3.4. Chromomycin, Mithramycin, and Other GC Binders.

3.5. Groove Binding and Intercalation.

4. Covalent Bonding Drugs.

4.1. (+) CC1065 and Related Drugs.

4.2. Anthramycin and Tomaymycin.

4.3. Ecteinascidins.

4.4. Mitomycins.

4.5. Intercalating Alkylators.

5. Strand-Breaking Drugs.

5.1. Bleomycins.

5.2. Enediyne Antibiotics.

6. Metal-Containing Drugs.

6.1. Cisplatin.

6.2. Cisplatin Derivatives.

6.3. Transplatin and Derivatives.

6.4. Monofunctional Platinum Complexes.

6.5. Polynuclear and High-valent Platinum Complexes.

6.6. Complexes Containing Other Metals.

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Kazuo Nakamoto,Masamichi Tsuboi,Gary D Strahan,Interactions