Sale!

Edhf 2000 1st Edition by Paul Vanhoutte 0415269040 9780415269049

Original price was: $50.00.Current price is: $35.00.

Edhf 2000 1st Edition Paul M. Vanhoutte Digital Instant Download

Author(s): Paul M. Vanhoutte
ISBN(s): 9780415269049, 0415269040
Edition: 1
File Details: PDF, 8.22 MB
Year: 2001
Language: english
SKU: EB-1771536 Category: Tag:

Edhf 2000 1st Edition by Paul Vanhoutte – Ebook PDF Instant Download/Delivery: 0415269040, 9780415269049

Full download Edhf 2000 1st Edition after payment

Product details:

ISBN 10: 0415269040 

ISBN 13: 9780415269049

Author: Paul M. Vanhoutte

Understanding the nature and role of endothelium-derived hyperpolarizing factor appears to be crucial in the quest for improved treatments for hypertension, diabetes, ischemia-reperfusion and other vascular disorders. EDHF 2000 comprises the proceedings of the Third International Symposium on endothelium-dependent hyperpolarizations. The first two meetings established a role for EDHF and other chemical factors involved in endothelium-dependent hyperpolarizations. These proceedings focus upon the role of gap junctions in cardiovascular responses and investigate the chemical identity of EDHF. Additional chapters on Physiology, Hormonal Modulation and Pathological Changes are also included. EDHF 2000 will be of interest not only to physiologists and pharmacologists puzzled by the complexity of the interactions between the endothelium and underlying vascular smooth muscle cells, but also clinical researchers and physicians treating patients with cardiovascular diseases.

Table of contents:

  1. What do gap junctions do anyway?

  2. Cardiovascular gap junctions: functional diversity, complementation and specialization of connexins

  3. Endothelium and smooth muscle pathways for conduction along resistance microvessels

  4. Membrane potential and calcium responses evoked by acetylcholine in submucosal arterioles of the guinea-pig small intestine

  5. The effects of ouabain, 18α-glycyrrhetinic acid and connexin-mimetic peptides on intercellular communication in cells expressing a Cx43-GFP chimeric protein

  6. Role of gap junctions in endothelium-dependent hyperpolarizations

  7. Heterogeneity of EDHF-type relaxations of rabbit and rat arteries analysed with peptides homologous to the extracellular loops of connexins 37, 40 and 43

  8. Myoendothelial and circumferential spread of endothelium-dependent hyperpolarization in coronary arteries

  9. Direct myoendothelial contacts in human pulmonary microvessels

  10. Role of gap junctional communication in EDHF-mediated responses and mechanisms of K⁺-induced dilatations

  11. Comparison of α and β isoforms of glycyrrhetinic acid and carbenoxolone as inhibitors of EDHF-type relaxation

  12. Inhibitory effect of 18-glycyrrhetinic acid on the relaxation induced by acetylcholine in the rat aorta

  13. A central role for endothelial cell potassium channels in EDHF-mediated responses

  14. Could the EDHF be K⁺ in porcine coronary arteries?

  15. Nitro-L-arginine/indomethacin-resistant relaxations to acetylcholine in small gastric arteries of the rat: Effect of ouabain plus Ba²⁺ and relation to potassium ions

  16. Effects of barium, ouabain and K⁺ on the resting membrane potential and endothelium-dependent responses in rat arteries

  17. EDHF and potassium: blockade of chloride channels reveals relaxations of rat mesenteric artery to potassium

  18. Cytochrome P450 2C – a source of EDHF and reactive oxygen species in the porcine coronary artery

  19. Cortisol increases EDHF-mediated relaxations in porcine coronary arteries and up-regulates the expression of cytochrome P450 2C9

  20. An arachidonic acid metabolite(s) produced by the endothelial cytochrome P450 isoform, CYP3A4, relaxes the lingual artery of the monkey via K⁺ channel opening

  21. EDHF-mediated responses induced by bradykinin in the porcine coronary artery

  22. Epoxyeicosatrienoic acid release mediates nitric oxide-independent dilatation of rat mesenteric vessels

  23. Epoxyeicosatrienoic acid and endothelium-dependent hyperpolarization in porcine coronary arteries

  24. Lipoxygenase-derived metabolites of arachidonic acid are not involved in the endothelium-dependent hyperpolarization to acetylcholine in the carotid artery of the guinea-pig

  25. Cytochrome P450 isoforms in the brain encode cell specific hyperpolarizing factors with a common mechanism of action

  26. Expression of recombinant cytochrome P450 epoxygenase in rat brain

  27. Identification of 11,12,15-trihydroxyeicosatrienoic acid as the mediator of acetylcholine- and arachidonic acid-induced relaxations in the rabbit aorta

  28. Identification of hydrogen peroxide as an endothelium-derived hyperpolarizing factor in mice

  29. Components of the potassium currents underlying the actions of endothelium-derived hyperpolarizing factor in arterioles

  30. Evidence for relaxation to endothelium-derived hyperpolarizing factor (EDHF) in isolated small mesenteric arteries of the mouse

  31. Pharmacological characterization of potassium channels in intact mesenteric arteries and single smooth muscle cells from eNOS -/- and +/+ mice

  32. EDHF, which is not NO, is a major endothelium-dependent vasodilator in mice

  33. Prostacyclin and iloprost in the isolated carotid artery of the guinea-pig

  34. Role of charybdotoxin/apamin sensitive K⁺Ca channels in pulsatile perfusion-mediated coronary vasodilatation in vivo

  35. Essential role of estrogen in the EDHF-mediated responses of mesenteric arteries from middle-aged female rats: possible contribution of gap junctional protein connexin43

  36. Endothelium-derived hyperpolarizing factor (EDHF) and utero-feto-placental circulation in the rat

  37. Endothelium-derived hyperpolarizing factor maintains a normal relaxation to bradykinin despite impairment of the nitric oxide pathway in porcine coronary arteries with regenerated endothelium

  38. Mechanisms underlying the vasodilatation caused by bradykinin in essential hypertensive patients

  39. Influence of diabetes on endothelium-dependent responses in mesenteric and femoral arteries of rats

  40. Folate restores the NO synthase- and cyclooxygenase-resistant renal vasodilator response to acetylcholine in diabetes

  41. Resistance of EDHF-mediated relaxations to oxidative stress in human radial arteries

  42. Critical limb ischemia results in different types of endothelial dysfunction depending on the vascular bed studied

  43. Potentiated EDHF-mediated dilatations in the rat middle cerebral artery following ischemia/reperfusion

  44. The EDHF-dependent but not the NO-dependent component of the acetylcholine-induced relaxation of the rabbit aorta is resistant to ionized radiation

  45. Inhibition of converting enzyme prevents the age-related decline in endothelium-dependent hyperpolarization

  46. Effects of a converting enzyme inhibitor, an AT1-receptor antagonist and their combination on endothelial dysfunction in hypertension

  47. EDHF: gap junction or chemical? and many other questions

People also search:

ad 2000-m

bf-2000

2000 b.c.e

2000-b

2000 c.e

Tags: Paul Vanhoutte, Edhf 2000