Energy Metabolism and Lifespan Determination 1st Edition by Mattson 0444514929 9780444514929

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Product details:

ISBN 10: 0444514929

ISBN 13: 9780444514929

Author: M.P. Mattson

 Experts in the fields of energy metabolism, aging and oxidative stress provide an integrated view of how mechanisms involved in regulating energy metabolism are linked to fundamental processes of aging including cellular stress resistance and free radical production.
During evolution signal transduction pathways and organ systems have been optimised for the efficient seeking, ingestion, storing and using of energy. These signalling pathways play prominent roles in lifespan determination with insulin and related signalling pathways being prime examples. The authors consider how lifespan and healthspan can be extended through knowledge of energy metabolism with the experimental model of dietary restriction being one example. The information in this volume of ACAG will foster novel approaches and experiments for further understanding the roles of energy metabolism in aging and disease.

Energy Metabolism and Lifespan Determination 1st Table of contents:

Chapter 1. The Search for Energy: A Driving Force in Evolution and Aging

Chapter 2. Insulin Signaling, Glucose Metabolism Oxidative Stress, and Aging

Chapter 3. Oxidative Phosphorylation, Mitochondrial Proton Cycling, Free-radical Production and Agin

Chapter 4. Protein Turnover, Energy Metabolism, Aging, and Caloric Restriction

Chapter 5. Cellular and Molecular Mechanisms Whereby Dietary Restriction Extends Healthspan: A Benef

Chapter 6. Mitochondrial Oxidative Stress and Caloric Restriction

Chapter 7. Understanding the Aging Fly Through Physiological Genetics

Chapter 8. Metabolism and Life span Determination in C. elegans

Chapter 9. Electron Transport and Life span in C. elegans

Chapter 10. Cellular Glucose Sensing, Energy Metabolism, and Aging in Saccharomyces cerevisiae

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Tags: Mattson, Energy, Metabolism, Lifespan, Determination