Genetic Toxicology Testing A Laboratory Manual 1st Edition by Ray Proudlock – Ebook PDF Instant Download/Delivery: 9780128007648, 0128007648
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Product details:
ISBN 10: 0128007648
ISBN 13: 9780128007648
Author: Ray Proudlock
Genetic Toxicology Testing: A Laboratory Manual presents a practical guide to genetic toxicology testing of chemicals in a GLP environment. The most commonly used assays are described, from laboratory ad test design to results analysis. In a methodical manner, individual test methods are described step-by-step, along with equipment, suggested suppliers, recipes for reagents, and evaluation criteria.
An invaluable resource in the lab, this book will help to troubleshoot any assay problems you may encounter to optimise quality and efficiency in your genetic toxicology tests. Genetic Toxicology Testing: A Laboratory Manual is an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own.
- Offers practical and consistent guidance on the most commonly-performed tests and procedures in a genetic toxicology lab
- Describes standard genetic toxicology assays, their methodology, reagents, suppliers, and analysis of their results
- Includes guidance on general approaches: formulation for in vitro assays, study monitoring, and Good Laboratory Practice (GLP)
- Serves as an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own lab
Table of contents:
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A Practical Guide to Genetic Toxicology Testing
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General Recommendations
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Formulation of Test Articles
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The Bacterial Reverse Mutation Test
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The Mouse Lymphoma TK Assay
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The In Vitro Micronucleus Assay
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The In Vitro Chromosome Aberration Test
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The In Vivo Rodent Micronucleus Assay
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The Rodent Bone Marrow Chromosomal Aberration Test
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The In Vivo Comet Assay Test
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The Pig-a Endogenous Gene Mutation Assay
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Tags: Ray Proudlock, Genetic, Toxicology, Testing, Laboratory