Handbook of Biosensors and Biochips 1st Edition by Robert S Marks, Christopher R Lowe – Ebook PDF Instant Download/Delivery: 0470019050, 9780470019054
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Product details:
ISBN 10: 0470019050
ISBN 13: 9780470019054
Author: Robert S Marks, Christopher R Lowe
Handbook of Biosensors and Biochips 1st Table of contents:
Part I: Introduction to Biosensor and Biochip Technologies
Chapter 1: Fundamentals of Biosensing and Biochips
- 1.1 Defining Biosensors: Components and Principles
- 1.2 The Evolution of Biosensor Technology
- 1.3 What are Biochips and Microarrays?
- 1.4 Key Performance Parameters: Sensitivity, Selectivity, Detection Limit
- 1.5 Classification of Biosensors and Biochips
Chapter 2: Biological and Molecular Recognition Systems (Bioreceptors)
- 2.1 Enzymes as Biorecognition Elements: Principles and Applications
- 2.2 Antibodies and Immunoassays: Immunosensors
- 2.3 Nucleic Acids: DNA, RNA, and Aptamers in Sensing
- 2.4 Cell-Based Biosensors: Whole-Cell Bioreporters
- 2.5 Receptors, Peptides, and Other Biorecognition Molecules
- 2.6 Biomimetic Recognition Elements: Molecularly Imprinted Polymers (MIPs)
Part II: The Biology-Materials Interface: Interfacial Science and Receptor Integration
Chapter 3: Principles of Interfacial Science for Biosensors
- 3.1 Surface Chemistry and Bio-Interactions
- 3.2 Material Selection for Biosensing Platforms
- 3.3 Preventing Fouling and Non-Specific Binding
- 3.4 Surface Characterization Techniques for Biosensors
Chapter 4: Immobilization Strategies for Bioreceptors
- 4.1 Physical Adsorption and Encapsulation Methods
- 4.2 Covalent Binding and Cross-Linking Techniques
- 4.3 Self-Assembled Monolayers (SAMs) for Biosensor Surfaces
- 4.4 Electrochemical Polymerization for Biomolecule Immobilization
- 4.5 Micro- and Nanopatterning for Directed Immobilization
Chapter 5: Smart Materials and Hydrogels for Biosensing
- 5.1 Stimuli-Responsive Materials in Biosensors
- 5.2 Hydrogels: Properties and Applications in Sensing and Drug Delivery
- 5.3 Polymer-Based Biosensors and Flexible Electronics
- 5.4 Nanomaterials in Biosensors: Nanoparticles, Nanotubes, Nanosheets
Part III: Transducer Technologies for Biosensors and Bioarray Technologies
Chapter 6: Electrochemical Transduction
- 6.1 Potentiometric Biosensors: Ion-Selective Electrodes (ISEs) and Field-Effect Transistors (FETs)
- 6.2 Amperometric Biosensors: Principles and Applications
- 6.3 Conductometric and Impedimetric Biosensors
- 6.4 Voltammetric Techniques in Biosensing
- 6.5 Microelectrode Arrays for Electrochemical Detection
Chapter 7: Optical Transduction Methods
- 7.1 Principles of Optical Biosensing: Absorption, Fluorescence, Luminescence
- 7.2 Surface Plasmon Resonance (SPR) Biosensors
- 7.3 Fiber Optic Biosensors
- 7.4 Colorimetric and Chemiluminescent Biosensors
- 7.5 Total Internal Reflection Fluorescence (TIRF) Microscopy in Biosensors
Chapter 8: Mass-Based and Mechanical Transduction
- 8.1 Quartz Crystal Microbalance (QCM) Biosensors
- 8.2 Surface Acoustic Wave (SAW) Devices
- 8.3 Cantilever-Based Biosensors and Micro-Electromechanical Systems (MEMS)
- 8.4 Micromechanical Resonators for Label-Free Detection
- 8.5 Piezoelectric Biosensors
Chapter 9: Thermal and Other Transduction Principles
- 9.1 Principles of Calorimetric Biosensors
- 9.2 Thermoelectric Devices in Biosensing
- 9.3 Emerging Transduction Mechanisms: Magnetic, Acoustic, etc.
Volume 2
Part IV: Miniaturized, Micro-engineered, and Particle Systems
Chapter 10: Microfluidics and Lab-on-a-Chip Devices
- 10.1 Principles of Microfluidic Design and Fabrication
- 10.2 Microfluidic Components: Pumps, Valves, Mixers
- 10.3 Integration of Biosensors with Microfluidic Platforms
- 10.4 Applications of Lab-on-a-Chip in Diagnostics and Analysis
- 10.5 Droplet-Based Microfluidics
Chapter 11: Bio-MEMS and Nanofabrication for Biosensors
- 11.1 Micro-Electromechanical Systems (MEMS) in Biosensors
- 11.2 Nanofabrication Techniques for Biosensing (e.g., electron beam lithography, self-assembly)
- 11.3 Nanoparticles and Quantum Dots in Biosensing
- 11.4 Integration of Nanomaterials into Biosensor Architectures
Part V: Array Technologies and High-Throughput Screening
Chapter 12: DNA Microarrays and Gene Expression Profiling
- 12.1 Principles of DNA Microarray Technology
- 12.2 Fabrication and Detection Methods for DNA Chips
- 12.3 Applications in Gene Expression, Genotyping, and Diagnostics
- 12.4 Data Analysis and Bioinformatics for Microarray Data
Chapter 13: Protein Microarrays and Proteomics
- 13.1 Principles of Protein Array Fabrication and Detection
- 13.2 Applications in Biomarker Discovery, Protein Interaction Studies, and Diagnostics
- 13.3 Challenges in Protein Array Development and Standardization
Chapter 14: Cell-Based Arrays and Organ-on-a-Chip
- 14.1 Microarrays for Cell Adhesion, Proliferation, and Differentiation Studies
- 14.2 3D Cell Culture Systems and Their Integration with Biosensors
- 14.3 Organs-on-a-Chip: Mimicking Human Physiology for Drug Testing
Part VI: Data Analysis, Conditioning, and Presentation
Chapter 15: Signal Processing and Data Interpretation
- 15.1 Noise Reduction and Signal Amplification Techniques
- 15.2 Calibration and Standardization of Biosensor Signals
- 15.3 Chemometrics and Multivariate Data Analysis for Complex Biosensing Data
- 15.4 Machine Learning and Artificial Intelligence in Biosensor Data Analysis
Chapter 16: Biosensor System Integration and Readout Devices
- 16.1 Design of Integrated Biosensor Systems
- 16.2 Portable and Handheld Readout Devices
- 16.3 Wireless Biosensors and Remote Monitoring
- 16.4 Data Visualization and User Interfaces
Part VII: Areas and Examples of Biosensor Applications
Chapter 17: Medical Diagnostics and Personalized Medicine
- 17.1 Point-of-Care (POC) Diagnostics
- 17.2 Glucose Monitoring and Diabetes Management
- 17.3 Cancer Biomarker Detection
- 17.4 Infectious Disease Diagnostics
- 17.5 Personalized Medicine and Theranostics
Chapter 18: Environmental Monitoring
- 18.1 Water Quality Monitoring: Pollutants and Toxins
- 18.2 Air Quality Monitoring
- 18.3 Soil Contamination Detection
- 18.4 Biosensors for Bioremediation Monitoring
Chapter 19: Food Safety and Quality Control
- 19.1 Pathogen Detection in Food
- 19.2 Allergen Detection
- 19.3 Quality Assessment of Food Products
- 19.4 Pesticide and Chemical Residue Detection
Chapter 20: Drug Discovery and Pharmaceutical Research
- 20.1 High-Throughput Screening with Biosensor Arrays
- 20.2 Drug-Target Interaction Studies
- 20.3 Toxicity Testing and ADMET Profiling
- 20.4 Cell-Based Assays for Pharmaceutical Development
Chapter 21: Biodefense and Security Applications
- 21.1 Detection of Biological Warfare Agents
- 21.2 Pathogen Identification in Threat Scenarios
- 21.3 Rapid Response Systems and Field-Deployable Sensors
Part VIII: Commercialization, Business, and Regulatory Issues
Chapter 22: From Lab to Market: Commercialization Strategies
- 22.1 Intellectual Property and Patenting in Biosensors
- 22.2 Funding and Investment for Biosensor Startups
- 22.3 Business Models for Biosensor Products
- 22.4 Case Studies of Successful Commercialization
Chapter 23: Regulatory Landscape for Biosensors and Biochips
- 23.1 FDA Approval Processes for Medical Devices
- 23.2 European Regulations (CE Marking)
- 23.3 Quality Management Systems (e.g., ISO Standards)
- 23.4 Ethical Considerations in Biosensor Development and Use
Part IX: Future Implications, Trends, and Perspectives
Chapter 24: Emerging Technologies and Future Directions
- 24.1 Wearable and Implantable Biosensors
- 24.2 Non-Invasive Biosensing Techniques
- 24.3 Integration of Biosensors with Artificial Intelligence and IoT
- 24.4 Synthetic Biology and Biosensor Design
- 24.5 Miniaturization, Multiplexing, and System Integration
Chapter 25: Societal Impact and Ethical Considerations
- 25.1 Personalized Health and Data Privacy
- 25.2 Equity of Access to Advanced Diagnostic Technologies
- 25.3 Biosecurity and Dual-Use Technologies
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Tags: Robert S Marks, Christopher R Lowe, Handbook, Biosensors