Handbook of the biology of aging 7th Edition by Masoro E ISBN 012378638X 9780123786388

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ISBN 10: 012378638X 
ISBN 13: 9780123786388
Author: Masoro

Handbook of the Biology of Aging, Seventh Edition, reviews and synthesizes recent findings and discoveries in the field. This volume is part of The Handbooks of Aging series, which also includes The Handbook of the Psychology of Aging and The Handbook of Aging and the Social Sciences.

The book is organized into two parts. Part 1 covers basic aging processes. It covers concepts relevant to clinical research, such as muscle, adipose tissue, and stem cells. It discusses research on how dietary restriction can slow down the aging process and extend life in a wide range of species. Part 2 deals with the medical physiology of aging. It contains several chapters on the aging of the human brain. These chapters deal not only with diseases but also with normal aging changes to cerebral vasculature and myelination as well as the clinical implications of those changes. Additional chapters cover how aging affects central features of human health such as insulin secretion, pulmonary and cardiac function, and the ability to maintain body weight and body temperature.
The volume is primarily directed at basic researchers who wish to keep abreast of new research outside their own subdiscipline. It will also be useful to medical, behavioral, and social gerontologists who want to learn about the discoveries of basic scientists and clinicians.

Handbook of the biology of aging 7th Table of contents:

Part 1: Basic Aging Processes
Chapter 1: The Genetic Network of Life-Span Extension by Dietary Restriction
Chapter 2: Role of the Somatotropic Axis in Mammalian Aging
Chapter 3: Mechanisms of Mitochondrial Free Radical Production and their Relationship to the Aging Process
Chapter 4: Aging and Apoptosis in Muscle
Chapter 5: Aging and Adipose Tissue
Chapter 6: Aging of Stem Cells: Intrinsic Changes and Environmental Influences
Chapter 7: Leukocyte Telomere Dynamics, Human Aging, and Life Span
Chapter 8: An Objective Appraisal of the Free Radical Theory of Aging
Chapter 9: TOR: A Conserved Nutrient-Sensing Pathway that Determines Life-Span Across Species
Chapter 10: Comparative Genetics of Aging
Chapter 11: Sirtuins in Aging and Age-Related Diseases
Chapter 12: Inflammation in Aging Processes: An Integrative and Ecological Perspective
Chapter 13: Protein Homeostasis and Aging
Part 2: Medical Physiology of Aging
Chapter 14: Terminal Weight Loss, Frailty, and Mortality
Chapter 15: Human Brain Myelination Trajectories Across the Life Span: Implications for CNS Function and Dysfunction
Chapter 16: Aging and the Cerebral Microvasculature: Clinical Implications and Potential Therapeutic Interventions
Chapter 17: Aging and Insulin Secretion
Chapter 18: Cardiovascular Effects of Aging in Primates—Gender Differences
Chapter 19: Cerebral Vascular Dysfunction with Aging
Chapter 20: Pulmonary Function in Aging Humans
Chapter 21: Calorie Restriction in Nonhuman and Human Primates
Chapter 22: Age-Related Changes in Thermoreception and Thermoregulation
Chapter 23: Sex Differences in Longevity and Aging

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