Hazard assessment of ethylene oxide reprint 1986 1st Edition by Leon Golberg – Ebook PDF Instant Download/Delivery: 135107282X, 9781351072823
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Product details:
ISBN 10: 135107282X
ISBN 13: 9781351072823
Author: Leon Golberg
This is a very specific, likely highly technical, and possibly out-of-print scientific or industrial safety report. Reprints of such specialized documents often do not have their detailed tables of contents widely digitized or publicly available in standard book databases.
Hazard assessment of ethylene oxide reprint 1986 1st Table of contents:
Chapter 1: Chemical and Physical Properties of Ethylene Oxide
- Chemical structure and formula
- Physical state, boiling point, melting point, vapor pressure, solubility
- Flammability and explosivity hazards
- Reactivity and decomposition products
Chapter 2: Production, Use, and Environmental Release of Ethylene Oxide
- Industrial synthesis methods
- Major applications (e.g., sterilization of medical equipment, production of ethylene glycol, surfactants)
- Sources of environmental release (industrial emissions, fugitive emissions)
- Environmental fate and transport (air, water, soil)
Chapter 3: Toxicology of Ethylene Oxide
- Acute Toxicity:
- Routes of exposure (inhalation, dermal, ingestion)
- Symptoms of acute exposure (irritation, nausea, central nervous system effects)
- Lethal dose/concentration data (LD50, LC50)
- Subchronic and Chronic Toxicity:
- Effects on target organs (respiratory system, nervous system, reproductive system)
- Mutagenicity and genotoxicity studies (e.g., chromosomal aberrations, DNA adducts)
- Carcinogenicity studies (animal data, epidemiological studies on exposed workers – likely a major focus given the 1980s context)
- Reproductive and developmental toxicity
- Immunotoxicity
- Mechanism of Action:
- How EtO interacts with biological molecules (alkylation)
Chapter 4: Exposure Assessment
- Occupational exposure levels (industrial settings, hospitals)
- Environmental exposure levels (general population)
- Monitoring methods (air sampling, biological monitoring)
Chapter 5: Risk Characterization
- Quantitative risk assessment (if possible based on data)
- Qualitative risk assessment
- Comparison of exposure levels to known effect levels
- Uncertainty analysis
Chapter 6: Regulatory and Control Measures
- Existing occupational exposure limits (OSHA, ACGIH, etc.)
- Environmental regulations
- Best practices for handling and storage
- Engineering controls (ventilation, containment)
- Personal protective equipment (PPE)
- Emergency response procedures
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Tags: Leon Golberg, Hazard, assessment