Human Oncogenic Viruses 1st Edition by James Jing Hsiung Ou, Benedict Yen ISBN 9812833471 9789812833471

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Product details:

ISBN 10: 9812833471

ISBN 13: 9789812833471

Author:  James Jing-Hsiung Ou, Benedict Yen 

Human Oncogenic Viruses 1st Edition: Viruses are the causes of approximately 25% of human cancers. Due to their importance in carcinogenesis, there is a desperate need for a book that discusses these viruses. This book is therefore timely, providing a comprehensive review of the molecular biology of oncogenic viruses and the cancers they cause. Viruses that are discussed in the individual chapters include hepatitis B virus, hepatitis C virus, human papilloma viruses, Epstein-Barr virus, Kaposi’s sarcoma virus and human T-cell leukemia virus type 1.This book provides up-to-date information for graduate students, postdoctoral fellows, medical students, physicians and non-experts who are interested in learning more about the oncogenic viruses and how they cause human cancers.

 

Human Oncogenic Viruses 1st Edition Table of contents:

 

Chapter 1: Oncogenic Viruses, Cellular Transformation and Human Cancers

1. Introduction and Historical Aspects
2. Human Oncogenic Viruses
   • Hepatitis B Virus (HBV)
   • Hepatitis C Virus (HCV)
   • Human Papilloma Virus (HPV)
   • Epstein-Barr Virus (EBV)
   • Kaposi’s Sarcoma-associated Herpesvirus (KSHV)
   • Human T-cell Leukemia Virus-1 (HTLV-1)
3. Mechanisms of Virus-induced Cellular Transformation
4. Concluding Remarks
5. Bibliography

Chapter 2: Hepatitis B Virus and Hepatocellular Carcinogenesis

1. Hepatitis B Virus and Hepatocellular Carcinoma
2. Biology and Epidemiology of HBV
3. HBV Virology
4. Prevention and Treatment of HBV
5. Mechanisms of HBV Carcinogenesis
6. Summary
7. Note
8. References

Chapter 3: Molecular Mechanism of Hepatitis C Virus Carcinogenesis

1. Introduction
2. Molecular Carcinogenesis of HCV
3. Other Causative Factors in HCV-associated HCC
4. Endoplasmic Reticulum Stress and HCV Pathogenesis
5. Gene Expression Profile of HCC
6. HCV and Lymphomagenesis
7. Conclusions
8. References

Chapter 4: Human Papillomaviruses and Associated Malignancies

1. Introduction
2. Viral Life Cycle
3. Clinical Disease
4. Detection, Treatment, and Prevention
5. Carcinogenic Progression and Viral Oncoproteins
6. Genomic Instability in HPV-Associated Cancers
7. Concluding Remarks
8. References

Chapter 5: Epstein-Barr Virus and Its Oncogenesis

1. Introduction
2. EBNA1
3. EBNA2, EBNA3A, EBNA3B, EBNA3C, and EBNA-LP
4. LMP1 and Its Variants
5. LMP2A and LMP2B
6. EBERs
7. EBV-Encoded miRNA
8. Perspectives
9. References

Chapter 6: Human Kaposi’s Sarcoma-associated Herpesvirus: Molecular Biology and Oncogenesis

1. Introduction
2. Clinical Disease
3. KSHV Genome
4. Life Cycle
5. Viral Proteins Involved in Signal Transduction
6. Summary
7. Acknowledgments
8. References

Chapter 7: Human T-Cell Leukemia Virus 1 and Cellular Transformation

1. The Discovery of HTLV-1
2. Pleiotropic Functions of the HTLV-1 Oncoprotein Tax
3. Future Perspectives

 

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