Lipids and Atherosclerosis 1st Edition by Christopher Packard, Daniel John Rader – Ebook PDF Instant Download/Delivery: 9781842142295, 1842142291
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Product details:
ISBN 10: 1842142291
ISBN 13: 9781842142295
Author: Christopher J. Packard, Daniel John Rader
New discoveries in genetics, molecular, and cell biology are not only enhancing our understanding of the etiology and progression of disease, but are finding applications in the development of new drugs or the implementation of new kinds of therapy. This book provides an in-depth review of emerging areas in biomedical research at the interface
Table of contents:
1. The assembly of very low density lipoproteins in the liver
2. Cardiovascular implications of partial, tissue-specific silencing of MTP
3. Acyl CoA: Diacylglycerol acyltransferases (DGATs) as therapeutic targets for cardiovascular disease
4. The biochemical and physiological roles of ACAT1 and ACAT2 in cholesterol homeostasis and atherosclerosis
5. Overview of intestinal lipid metabolism
6. The role of non-cholesterol sterols in the pathogenesis of atherosclerosis and their modulation by the sitosterolaemia locus
7. FXR: the molecular link between bile acid and lipid metabolism
8. Overview of HDL and reverse cholesterol transport
9. LXR as a therapeutic target for atherosclerosis
10. Endothelial lipase and the regulation of HDL metabolism
11. Cholesteryl ester transfer protein (CETP) inhibition as a therapeutic strategy for raising HDL-cholesterol levels and reducing atherosclerosis
12. Overview of insulin resistance and the metabolic syndrome
13. Peroxisome proliferator activated receptors and energy metabolism
14. Adipocytes and their secretory products
15. Regulation of adipocyte triglyceride storage
16. Role of innate immunity in atherosclerosis: immune recognition, immune activation and the atherosclerotic process
17. Role of CD44 in atherogenesis and its potential role as a therapeutic target
18. Lipoxygenases: potential therapeutic target in atherosclerosis
19. Role of secretory phospholipase A
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Tags: Christopher Packard, Daniel John Rader, Lipids, Atherosclerosis


