Local Drug Delivery for Coronary Artery Disease Established and Emerging Applications 1st Edition by Edoardo Camenzind, Ivan De Scheerder – Ebook PDF Instant Download/Delivery: 9781841840451, 1841840459
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Product details:
ISBN 10: 1841840459
ISBN 13: 9781841840451
Author: Edoardo Camenzind, Ivan De Scheerder
Pioneers in the field, the editors have assembled an excellent team of contributors with extensive experience of threatened vessel closure and restenosis, acute thrombosis, hyperproliferative cellular response, stents and local drug delivery. Comprehensive and up-to-date, this reference provides fully up-to-date information on currently available methods of drug delivery, as well as illustrations of drug delivery methods with seventy-five color and seventy-five black and white photos throughout the book. With this impressive presentation of the most up-to-date methods and applications, as well as a range of photographs illustrating their implementation, this guide is an excellent resource for cardiologists, pharmacologists, cardiac surgeons, and trainees.
Table of contents:
1 The purpose of site-specific therapy
2 Local drug delivery: impact of pressure,substance characteristics, and stenting on drug transfer into the arterial wall
3 Catheter-based and stent-based treatment for coronary artery disease
4 The ClearWay™ microporous balloon catheter
5 The Dispatch® coronary infusion catheter
6 The Remedy™ PTCA dilatation infusion catheter
7 The Infiltrator™ angioplasty balloon catheter
8 The Infiltrator™ local drug delivery catheter
9 The needle catheter
10 Stent-mediated local drug delivery
11 Silicon carbide-coated stents
12 The Carbostent: a Carbofilm™-coated stent
13 The PC-coated BiodivYsio™ stent
14 PTFE-covered stents
15 Overview of drug delivery coatings
16 Phosphorylcholine (PC Technology™) coated stents as a drug delivery platform
17 Direct stent coating: an alternative for polymers?
18 Radioactive stents
19 Overview of potential drugs to inhibit in-stent restenosis
20 Direct antithrombins
21 Tissue factor inhibitors
22 Nitric oxide-related interventions and restenosis
23 Vitamin E and its multiple properties: anti, pro, and non-oxidative activities
24 The dexamethasone eluting stent
25 Antiinflammatory approaches to restenosis
26 The role of matrix metalloproteinase inhibitors after arterial injury
27 Methotrexate: a potential drug for stent-mediated local drug delivery: antiinflammatory and antiproliferative characteristics
28 Actin-skeleton inhibitors: potential candidates for local drug delivery in the prevention of in-stent restenosis?
29 Local delivery of antisense oligomers to c-myc for the prevention of restenosis
30 Site-specific delivery of cytostatic agents
31 Catheter-based delivery of NOS gene
32 Carbon-coated stents: diamond-like stent coatings
33 Long-term biocompatibility evaluation of poly-bis-trifluorethoxyphosphazene (PTFEP): a novel biodegradable polymer stent coating in a porcine coronary stent model
34 Biocompatibility evaluation of biosoluble stent coatings in a porcine coronary stent model
35 Glycoprotein (GP) IIb/IIIa receptor antagonist eluting stents
36 Activated protein C eluting stents
37 Local methylprednisolone (MP) delivery using a BiodivYsio phosphorylcholine (PC)-coated drug delivery stent reduces inflammation and neointimal hyperplasia in a porcine coronary stent model
38 Methotrexate-loaded BOBSC-coated coronary stents reduce neointimal hyperplasia in a porcine coronary model
39 Rapamycin eluting stents
40 Preclinical evaluation of tacrolimus-coated coronary stents
41 Local delivery of paclitaxel as a stent coating
42 Addition of cytochalasin D to a biodegradable oil stent coating inhibits intimal hyperplasia in a porcine coronary model
43 Vascular endothelial growth factor (VEGF) eluting stents
44 An advanced antisense for local vascular delivery for prevention of restenosis
45 Stent-based gene delivery
46 Catheter-based local heparin delivery
47 Local delivery of low molecular weight heparins
48 Local delivery of steroids before coronary stent implantation
49 Clinical studies with the Carbostent
50 Gold-coated stents
51 Heparin-coated stent trials
52 The Blue Medical 50% TEMPO coronary stent: preclinical studies and the first clinical pilot trial
53Dexamethasone: mode of action, preclinical, and clinical studies Ivan De Scheerder, Xiaoshun Liu, Yanming Huang, and Eric Verbeken
54 17ß-Estradiol eluting stents: a potential therapy in the prevention of restenosis
55 Batimastat: mode of action, preclinical, and clinical studies
56 The FIM trial: sirolimus eluting stents
57 Tacrolimus eluting stents
58 Everolimus eluting stents
59The Quanam drug eluting stent and the
60 The Boston Scientific paclitaxel eluting stent: TAXUS I and II
61 Clinical results with non-polymer based taxol eluting stents. The European evaLUation of pacliTaxel Eluting Stent (ELUTES) trial
62 Intrapericardial drug delivery for the prevention of restenosis
63 Alternatives to drug eluting stents: safety and efficacy of systemic delivery of antiproliferative therapy to reduce in-stent neointimal hyperplasia
64 Drug eluting stents: a critical perspective1
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Tags: Edoardo Camenzind, Ivan De Scheerder, Local, Delivery


