Modified Release Drug Delivery Technology 1st Edition by Michael Rathbone, Jonathan Hadgraft 0824708695 978-0824708696

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Product details:

ISBN 10: 0824708695
ISBN 13: 978-0824708696
Author:  Michael J. Rathbone, Jonathan Hadgraft

Describing formulation challenges and their solutions in the design, development, and commercialization of modified-release drugs delivery systems, this book contains eighty papers that review recent developments in design and manufacturing techniques. It includes detailed descriptions of extended release drug products for the oral, nasal, ophthalmic, pulmonary, vaginal, dermal and transdermal pathways. With the exception of the final section addressing regulatory issues, each section covers a particular route for drug delivery and opens with an overview of the anatomical, physiological, and pharmaceutical basics of each route before moving on to cover specific technologies.

Modified Release Drug Delivery Technology 1st Table of contents:

Chapter 1 | 10 pages
Oral Modified-Release Delivery Systems
By Susan A. Charman, William N. Charman

Chapter 2 | 10 pages
TIMERx Oral Controlled-Release Drug Delivery System
By Troy W. McCall, Anand R. Baichwal, John N. Staniforth

Chapter 3 | 14 pages
MASRx and COSRx Sustained-Release Technology
By Syed A. Altaf, David R. Friend

Chapter 4 | 14 pages
Procise: Drug Delivery Systems Based on Geometric Configuration
By Sham K. Chopra

Chapter 5 | 10 pages
RingCap Technology
By David A. Dickason, George P. Grandolfi

Chapter 6 | 18 pages
Smartrix System: Design Characteristics and Release Properties of a Novel Erosion-Controlled Oral Delivery System
By Horst G. Zerbe, Markus Krumme

Chapter 7 | 12 pages
TheriForm Technology
By Charles W. Rowe, Chen-Chao Wang, Donald C. Monkhouse

Chapter 8 | 12 pages
Accudep Technology for Oral Modified Drug Release
By S. S. Chrai, David R. Friend, G. Kupperblatt, R. Murari, Jackie Butler, T. Francis, Araz A. Raoof, Brian McKenna

Chapter 9 | 14 pages
Osmotically Controlled Tablets
By Patrick S. L. Wong, Suneel K. Gupta, Barbara E. Stewart

Chapter 10 | 10 pages
Three-Phase Pharmaceutical Form—THREEFORM—with Controlled Release of Amorphous Active Ingredient for Once-Daily Administration
By Janez Kerc

Chapter 11 | 10 pages
Two Concepts, One Technology: Controlled-Release and Solid Dispersions with Meltrex
By Jörg Breitenbach and Jon Lewis

Chapter 12 | 16 pages
DissoCubes—A Novel Formulation for Poorly Soluble and Poorly Bioavailable Drugs
By Rainer H. Müller, Claudia Jacobs, and Oliver Kayser

Chapter 13 | 26 pages
IDD Technology: Oral Delivery of Water-Insoluble Drugs Using Phospholipid Stabilized Microparticulate IDD Formulations
By Awadhesh K. Mishra, Michael G. Vachon, Pol-Henri Guivarc’h, Robert A. Snow, and Gary W. Pace

Chapter 14 | 14 pages
Liquid-Filled and -Sealed Hard Gelatin Capsule Technologies
By Ewart T. Cole

Chapter 15 | 12 pages
The Zydis Oral Fast-Dissolving Dosage Form
By Patrick Kearney

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Michael Rathbone,Jonathan Hadgraft,Modified Release,Drug Delivery