Molecular physiology and metabolism of the nervous system a clinical perspective 1st Edition by Gary Rosenberg 0195394275 9780195394276

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Product details:

ISBN 10: 0195394275 

ISBN 13: 9780195394276

Author: Gary A. Rosenberg

The molecular basis for the physiology of the brain has advanced enormously in the past twenty years with an influx of new information gleaned through technological developments in neuroimaging and molecular discoveries. Molecular Physiology and Metabolism of the Nervous System, authored by Gary A. Rosenberg, an authority on the physiology of brain fluids and metabolism, combines the classic physiology that dates back to the beginning of the nineteenth century with the advances in molecular sciences, providing a strong framework for understanding the diseases that are commonly treated by neurologists. Molecular Physiology and Metabolism of the Nervous System focuses on the current neuropathology and implications of cerebrospinal fluid diseases and diseases of the blood-brain barrier: how the two affect stroke, infection, brain tumors, and increased intracranial pressure. The book discusses the effects of blood flow in stroke and dementia, the disruption of the blood-brain barrier in neuroinflammation, and the dysfunction due to brain edema and increased intracranial pressure. Molecular Physiology and Metabolism of the Nervous System is necessary reading for neurologists, neuroscientists, and residents in neurology, neurosurgery, and psychiatry, giving them a strong grounding in physiology and metabolism that will aid them in diagnosis and treatment.

Table of contents:

PART 1 PHYSIOLOGY OF BRAIN FLUIDS AND THE BLOOD-BRAIN BARRIER
1. ANATOMY OF FLUID INTERFACES THAT PROTECT THE MICROENVIRONMENT
2. PHYSIOLOGY OF THE CEREBROSPINAL AND INTERSTITIAL FLUIDS
3. NEUROVASCULAR UNIT

PART 2 METABOLISM, DISORDERS OF BRAIN FLUIDS, AND MATHEMATICS OF TRANSPORT
4. GLUCOSE, AMINO ACID, AND LIPID METABOLISM
5. DISORDERS OF CEREBROSPINAL CIRCULATION: IDIOPATHIC INTRACRANIAL HYPERTENSION AND HYDROCEPHALUS
6. QUANTIFICATION OF CEREBRAL BLOOD FLOW AND BLOOD-BRAIN BARRIER TRANSPORT BY NUCLEAR MAGNETIC RESONANCE

PART 3 ISCHEMIA, EDEMA, AND INFLAMMATION
7. MECHANISMS OF ISCHEMIC/HYPOXIC BRAIN INJURY
8. VASCULAR COGNITIVE IMPAIRMENT AND ALZHEIMER’S DISEASE
9. EFFECTS OF ALTITUDE ON THE BRAIN
10. BRAIN EDEMA
11. INTRACEREBRAL HEMORRHAGE
12. AUTOIMMUNITY, HYPOXIA, AND INFLAMMATION IN DEMYELINATING DISEASES

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