Neuroscience of Nicotine Mechanisms and Treatment 1st Edition by Victor Preedy 9780128130353 0128130350

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Product details:

ISBN 10: 0128130350

ISBN 13: 9780128130353

Author: Victor R. Preedy

Neuroscience of Nicotine: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of nicotine addiction and its effects on the brain. Offering thorough coverage of all aspects of nicotine research, treatment, policy and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of nicotine misuse.

With an estimated one billion individuals worldwide classified as tobacco users—and tobacco use often being synonymous with nicotine addiction—nicotine is one of the world’s most common addictive substances, and a frequent comorbidity of misuse of other common addictive substances. Nicotine alters a variety of neurological processes, from molecular biology, to cognition, and quitting is exceedingly difficult because of the number of withdrawal symptoms that accompany the process.

• Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of nicotine use, along with its effects on neurobiological function
• Discusses nicotine use as a component of dual-use and poly addictions and outlines numerous screening and treatment strategies for misuse
• Covers both the physical and psychological effects of nicotine use and withdrawal to provide a fully-formed view of nicotine dependency and its effects

Table of contents:

1. Understanding Tobacco Use in Different Countries

2. Maternal Smoking and Fetal Brain Outcome: Mechanisms and Possible Solutions

3. Nicotine Effects in Adolescents

4. The Impact of Traditional Cigarettes and E-Cigarettes on the Brain

5. Reduction of Nicotine in Tobacco and Impact

6. Prenatal Nicotine Exposure and Neuronal Progenitor Cells

7. Synaptically Located Nicotinic Acetylcholine Receptor Subunits in Neurons

8. Cotinine as a Possible Allosteric Modulator of Nicotine Effects

9. Nicotine, Neural Plasticity, and Nicotine’s Therapeutic Potential

10. Habenular Synapses and Nicotine

11. Nicotine Neuroprotection of Brain Neurons: The Other Side of Nicotine Addiction

12. Linking Nicotine, Menthol, and Brain Changes

13. Cigarette Smoking and Nicotine: Effects on Multiple Sclerosis

14. Tobacco and PET Imaging of the Dopaminergic System

15. Resting-State Functional Connectivity Imaging and Nicotine Dependence

16. Functional Magnetic Resonance Imaging of Acute Nicotine Effects

17. Nicotine Dependence in Schizophrenia: Contributions of Nicotinic Acetylcholine Receptors

18. Attentional Bias and Smoking

19. Effects of Nicotine on Inhibitory Control in Humans

20. Nicotine, Corticotropin-Releasing Factor, and Anxiety-Like Behavior

21. 6-Hydroxy-l-Nicotine and Memory Impairment

22. Cotinine and Memory: Remembering to Forget

23. Nicotine in Aberrant Learning and Corticostriatal Plasticity

24. Prenatal Nicotine Exposure and Impact on the Behaviors of Offspring

25. Craving in Substance Use Disorders With a Focus on Cigarette Smoking

26. The Acute Effect of Exercise on Cravings and Withdrawal Symptoms

27. CRF2 Receptor Agonists and Nicotine Withdrawal

28. Delirium and Nicotine Withdrawal

29. Postoperative Nicotine Withdrawal

30. Nicotine and Alpha3β2 Nicotinic Acetylcholine Receptors

31. Nicotine Addiction and α4β2* Nicotinic Acetylcholine Receptors

32. The Medial Habenula-Interpeduncular Nucleus Pathway in Nicotine Sensitization

33. Targeting Nicotinic Acetylcholine Receptors for the Treatment of Pain

34. Pharmacology of Muscle-Type Nicotinic Receptors

35. Involvement of Opioid Receptors in Nicotine-Related Reinforcement and Pleasure

36. Nicotine-Induced Kindling: Influences of Age, Sex, and Prevention by Antioxidants

37. Nicotine Reward and Abstinence: Role of the CB1 Receptors

38. The Therapeutic Potential of the Cognitive-Enhancing Effects of Nicotine and Other Nicotinic Agonists

39. Nicotine and Dopamine D₁ Receptor Pharmacology

40. Brain Gene Expression in the Context of Nicotine Rewards: A Focus on Cholinergic Genes

41. HIV-Infected Subjects and Tobacco Smoking: A Focus on Nicotine Effects in the Brain

42. Renin-Angiotensin System Genes and Nicotine Dependence

43. Nicotine Dependence and the CHRNA5/CHRNA3/CHRNB4 Nicotinic Receptor Regulome

44. Brain, Nrf2, and Tobacco: Mechanisms and Countermechanisms Underlying Oxidative-Stress-Mediated Effects

45. Effects of Nicotine and Histone Deacetylase Inhibitors on the Brain

46. L-Type Calcium Channels and Nicotine

47. The Co-occurrence of Nicotine With Other Substance Use and Addiction

48. Comorbid Smoking and Gambling Disorder: Potential Underlying Mechanisms and Future Exploration

49. Neuroscience of Tobacco and Crack Cocaine Use: Metabolism, Effects, and Symptomatology

50. Salivary Cotinine Assays

51. Overview of Cotinine Cutoff Values for Smoking Status Classification

52. Smoking Abstinence Expectancies Questionnaire

53. Pharmacist-led Smoking Cessation Services: Current and Future Perspectives

54. Nicotine Use and Weight Control in Young People: Implications for Prevention and Early Intervention

55. Exercise as a Smoking Cessation Aid

56. Varenicline: Treating Smoking Addiction and Schizophrenia

57. Nicotine Vaccines: The Past, the Present, and the Future

58. Treating Nicotine Dependence in Psychiatric Hospitals

59. Oral 18-Methoxycoronaridine (18-MC) Decreases Nicotine Self-Administration in Rats

60. Pharmacogenetics and Smoking Cessation

61. The Orexin System and Nicotine Addiction: Preclinical Insights

62. Tobacco Control Policies and Smokers Responses

63. Resources for the Neuroscience of Nicotine

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Tags: Victor Preedy, Neuroscience, Nicotine, Mechanisms