Neurovirology 1st Edition by Alex Tselis, John Booss 9780702045394 070204539X

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ISBN 10: 070204539X
ISBN 13: 9780702045394 
Author: Alex C. Tselis and John Booss 

This volume in the Handbook of Clinical Neurology series provides a complete review of the history, science and current state of neurovirology. It covers the science and clinical presentation, diagnosis, and treatment of viruses of the brain and central nervous system, and is a trusted resource for scholars, scientists, neuroscientists, neurologists, virologists, and pharmacologists working on neurovirology.

Neurovirology has been significantly bolstered by modern technologies such as PCR and MRI with direct impact on isolating viruses and advancing therapeutics based on molecular medicine. These advances are particularly important today with the introduction of emerging and re-emerging diseases such as HIV/AIDS, Nipah encephalitis and the appearance of West Nile encephalitis in the western hemisphere.

*Detailed coverage of neurovirology from the basic science to clinical presentation

*Covers advances in neurovirology via polymerase chain reaction (PCR) and MRI technology

*Covers emerging and re-emerging diseases including HIV/AIDS, Nipah encephalitis, and the appearance of West Nile encephalitis in the western hemisphere

Neurovirology 1st Table of contents:

SECTION 1: Introduction
Chapter 1: A History of Viral Infections of the Central Nervous System: Foundations, Milestones, and Patterns

• Abstract
• Introduction
• Foundations
• Milestones
• Conclusions: Patterns Observed and Patterns Predicted

Chapter 2: Basics of Virology

• Abstract
• Introduction
• What Is a Virus?
• Virus Taxonomy and Nomenclature
• Virion Structure
• Virus Origins and Evolution
• Virus Replication Cycles
• Neurotropic Viruses
• Fundamental Aspects of Viral Pathogenesis
• Immunity to Viruses
• Diagnosis of Viral Infections
• Antivirals

Chapter 3: Neuroepidemiology and the Epidemiology of Viral Infections of the Nervous System

• Abstract
• Introduction
• Epidemiology of Viral Infections of the Nervous System
• Summary

Chapter 4: Clinical Approach to the Syndromes of Viral Encephalitis, Myelitis, and Meningitis

• Abstract
• Introduction
• Definitions of Viral CNS Infection Syndromes
• Viral Encephalitis
• Viral Meningitis
• Viral Myelitis
• Suggested Investigations for Viral CNS Infections
• Suggested Treatment for CNS Viral Infection

Chapter 5: Laboratory Diagnosis of Viral Infection

• Abstract
• Introduction
• General Principles of Laboratory Viral Diagnosis
• Viral Diagnostic Methods
• Sample Collection and Transport
• Summary and Interpretation of Test Results

Chapter 6: Neuroimaging of Viral Infections of the Central Nervous System

• Abstract
• Basic Principles of Imaging
• Herpesviruses
• Arbovirus
• Nipah and Hendra Virus
• Adenovirus
• Arenaviruses
• Hepatitis C
• Human Immunodeficiency Virus
• Progressive Multifocal Leukoencephalopathy
• Human T-Lymphotropic Virus Type I (HTLV-I)
• Acute Disseminated Encephalomyelitis
• Subacute Sclerosing Panencephalitis (SSPE)
• Rabies Encephalitis
• Mumps Encephalitis
• Enteroviral Encephalitis
• Influenza
• Conclusion

Chapter 7: Viral Neuropathogenesis

• Abstract
• Principles of Viral Pathogenesis
• Viral Invasion and Spread to the CNS
• Sites of Replication in the CNS
• Viral Strains
• Immune Response and Protection
• Virus-Induced Immunopathology of the Nervous System
• Persistent Viral Infections of the CNS

Chapter 8: Neuropathology of Viral Infections

• Abstract
• General Pathologic Features of Viral Encephalitis
• CNS Viral Infections Typically Presenting as an Acute Illness
• CNS Viral Infections Typically Associated with a Subacute or Chronic Course
• Acknowledgments

Chapter 9: Innate Immune Viral Recognition: Relevance to CNS Infections

• Abstract
• Innate Immune Signaling Pathways
• Cellular Components of the Innate Immune Response
• Innate Immune Responses in CNS Viral Infections
• Summary

Chapter 10: Adaptive Immune Response to Viral Infections in the Central Nervous System

• Abstract
• Viral Infection
• Adaptive Immune Response: General
• Adaptive Immune Response: Outside the CNS
• Adaptive Immune Response: Inside the CNS
• Viral Clearance vs. Viral Persistence
• Adaptive Immune Response to Specific Neurotropic Viruses
• Conclusion
• Acknowledgment

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Alex Tselis, John Booss,Neurovirology