New Developments in Sickle Cell Disease Research 1st Edition by P D O’Malley ISBN 1594547920 9781594547928
Original price was: $50.00.$35.00Current price is: $35.00.
New Developments in Sickle Cell Disease Research 1st Edition by P. D. O’Malley – Ebook PDF Instant Download/Delivery: 1594547920, 9781594547928
Full download New Developments in Sickle Cell Disease Research 1st Edition after payment
Product details:
ISBN 10: 1594547920
ISBN 13: 9781594547928
Author: P. D. O’Malley
Sickle cell anaemia is an inherited blood disorder, characterised primarily by chronic anaemia and periodic episodes of pain and occurring in approximately 1 in every 400 African-American infants born in the United States each year. Individuals of Mediterranean, Arabian, Caribbean, South and Central American, and East Indian ancestry can also be affected. The underlying problem involves haemoglobin, a component of the red cells in the blood. The haemoglobin molecules in each red blood cell carry oxygen from the lungs to the body organs and tissues and bring back carbon dioxide to the lungs. In sickle cell anaemia, the haemoglobin is defective. After the haemoglobin molecules give up their oxygen, some of them may cluster together and form long, rod-like structures. These structures cause the red blood cells to become stiff and to assume a sickle shape. Unlike normal red cells, which are usually smooth and donut-shaped, the sickled red cells cannot squeeze through small blood vessels. Instead, they stack up and cause blockages that deprive the organs and tissue of oxygen-carrying blood. This process produces the periodic episodes of pain and ultimately can damage the tissues and vital organs and lead to other serious medical problems. Unlike normal red blood cells, which last about 120 days in the bloodstream, sickled red cells die after only about 10 to 20 days. Because they cannot be replaced fast enough, the blood is chronically short of red blood cells, a condition called anaemia. Sickle cell anaemia is caused by an error in the gene that tells the body how to make haemoglobin. The defective gene tells the body to make the abnormal haemoglobin that results in deformed red blood cells. This book gathers the latest research in this important field.
Table of contents:
Chapter I: Malaria Resistance or Susceptibility in Red Cells Disorders
Chapter II: Resonant Raman Studies on Functional Erythrocytes
Chapter III: An Additional Copy of Chromosome 21 Drives Your Genes Wild
Chapter IV: Psychobiological Reactivity in Children with Sickle Cell Disease: A Novel Variable for Prediction of Outcomes and Improving Interventions
Chapter V: Acute Chest Syndrome in Sickle Cell Disease: Pathophysiologic Approach to Management
Chapter VI: A Decade of Advances in Sickle Cell Disease Management
Chapter VII: The Heart in Sickle Cell Disease
Chapter VIII: Oral Health Status and Anthropometric Findings in Sickle Cell Disease
People also search for:
new developments in sickle cell disease research
5 types of sickle cell crisis
recent advances in sickle cell disease
new cure for sickle cell disease
new advances in sickle cell disease treatment
Tags: P D O’Malley, Sickle Cell Disease, Medical Research, Hematology