Nuclear Receptor Coregulators And Human Diseases 1st Edition by Bert O’Malley, Rakesh Kumar 9789812705365 9812705368
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Product details:
ISBN 10: 9812705368
ISBN 13: 9789812705365
Author: Bert W. O’Malley, Rakesh Kumar
This book serves as a treasure for all those who have an interest in nuclear receptor coregulators and human diseases. Written by experts in the field, each chapter provides comprehensive, up-to-date information on the physiologic and pathologic roles of coregulators in specific organ systems, giving biomedical students; basic and clinical researchers; and educators in diverse sub-specialties a thorough summary of the overall subject. Readers will be able to understand the important current information and views on specific coactivators and corepressors and their roles in the pathogenesis of human diseases in areas outside their own expertise or experience. A special emphasis is placed on the “classic” papers as well as perspectives on future directions for the field.
Table of contents:
Chapter 1. Nuclear Receptor Coregulators in Human Diseases
Chapter 2. p160 Coactivators: Critical Mediators of Transcriptional Activation by Nuclear Receptors
Chapter 3. Regulation of Nuclear Hormone Receptor Functions by Ubiquitin-Proteasome Pathway
Chapter 4. Coregulators as Oncogenes and Tumor Suppressors
Chapter 5. A Central Role of SRC-3/AIB1 in Tumorigenesis
Chapter 6. Thyroid Hormone Receptors, Coregulators, and Disease
Chapter 7. Androgen Receptor Coactivators in Prostate Cancer
Chapter 8. PGC-1α and Metabolic Control in Skeletal and Cardiac Muscle
Chapter 9. Coregulators in Metabolic and Neurodegenerative Diseases
Chapter 10. Role of the RIP140 Corepressor in Metabolic Regulation
Chapter 11. Nuclear Receptor Corepressors and Metabolism
Chapter 12. Coregulators in CNS Function and Disease
Chapter 13. Tissue Repair and Cancer Control through PPARs and Their Coregulators
Chapter 14. Coregulators and Inflammation
Chapter 15. Nuclear Receptor Coactivators in the Cardiovascular System
Chapter 16. Coregulators as Determinants of Selective Receptor Modulator (SRM) Activity
Chapter 17. Coregulators in Toxicology
Chapter 18. Nuclear Receptor Coactivators Co-ordinate Metabolic Responses to Hormonal and Environmental Cues
Chapter 19. Nuclear Receptor Cofactor Interactions as Targets for New Drug Discovery
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Tags: Bert O’Malley, Rakesh Kumar, Nuclear, Coregulators