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Principles and Practice of Clinical Electrophysiology of Vision 2nd Edition by John Heckenlively 9780262083461

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Principles and Practice of Clinical Electrophysiology of Vision 2nd Edition John R. Heckenlively Digital Instant Download

Author(s): John R. Heckenlively, Geoffrey B. Arden (Editors)
ISBN(s): 9781423784159, 1423784154
Edition: second edition
File Details: PDF, 32.24 MB
Year: 2006
Language: english
SKU: EB-1707082 Category: Tags: ,

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ISBN 13: 9780262083461

Author: John R. Heckenlively

The long-awaited second edition of an authoritative reference on electrophysiologic vision testing, including detailed information on techniques and problems, basic physiology and anatomy, theoretical concepts, and clinical findings; with extensive new material.

This authoritative text is the only comprehensive reference available on electrophysiologic vision testing, offering both practical information on techniques and problems as well as basic physiology and anatomy, theoretical concepts, and clinical correlations. The second edition, of the widely used text, offers extensive new material and updated information: 65 of the 84 chapters are completely new, with the changes reflecting recent advances in the field. The book will continue to be an essential resource for practitioners and scholars from a range of disciplines within vision science.

The contributions not only cover new information—important material that is likely to become more important in the next decade—but also offer a long-range perspective on the field and its remarkable development in the last century. After discussing the history and background of clinical electrophysiology, the book introduces the anatomy of the retina and principles of cell biology in the visual pathways at the molecular, physiological, and biochemical levels. It relates these new findings to the techniques and interpretations of clinical tests, including the electro-oculogram (EOG), electroretinogram (ERG), and visual evoked potentials (VEP), which are discussed in detail, as are equipment, data acquisition and analysis, principles and protocols for clinical testing, diseases and dysfunction, and animal testing. Notable additions for this edition include chapters on the origin of electroretinogram waveforms, multifocal techniques, testing in standard laboratory animals, recent advances in analysis of abnormalities in disease, and the applications of these techniques to the study of genetic abnormalities.

Principles and Practice of Clinical Electrophysiology of Vision 2nd Table of contents:

 

I: HISTORY AND BACKGROUND TO MODERN TESTING

  1. History of the Electroretinogram
  2. History of Electro-Oculography
  3. History of Visual Evoked Cortical Testing

II: ANATOMY OF THE RETINA, PRINCIPLES OF CELL BIOLOGY IN THE VISUAL PATHWAYS: FUNCTIONAL, PHYSIOLOGICAL, BIOCHEMICAL, MOLECULAR, BIOLOGICAL

  1. The Photoreceptor–Retinal Pigment Epithelium Interface
  2. Membrane Mechanisms of the Retinal Pigment Epithelium
  3. Functional Organization of the Retina
  4. Phototransduction and Photoreceptor Physiology
  5. Synaptic Transmission: Sensitivity Control Mechanisms
  6. Structure and Function of Retinal Synapses: Role of Cell Adhesion Molecules and Extracellular Matrix
  7. Central Disorders of Vision in Humans

III: ORIGINS OF SLOW ELECTROPHYSIOLOGICAL COMPONENTS

  1. Origin and Significance of the Electro-Oculogram
  2. Origins of the Electroretinogram
  3. The Origin of the Pattern Electroretinogram
  4. The Multifocal Electroretinographic and Visual Evoked Potential Techniques
  5. Origin of the Visual Evoked Potentials

IV: EQUIPMENT

  1. Data Acquisition Systems for Electrodiagnostic Testing
  2. Electrodes for Visual Testing
  3. Amplifiers and Special-Purpose Data Acquisition Systems
  4. Stimulus Devices, Calibration, and Measurement of Light

V: DATA ACQUISITION

20.1 Introduction to the ISCEV Standards
20.2 EOG Standard
20.3 Standard for Clinical Electroretinography
20.4 Standard for Pattern Electroretinography
20.5 Visual Evoked Potentials Standard
20.6 Guidelines for Basic Multifocal Electroretinography
21. Multifocal Techniques
22. The Pattern Electroretinogram
23. Assessing Infant Acuity, Fusion, and Stereopsis with Visual Evoked Potentials
24. Aging and Pattern Visual Evoked Cortical Potential
25. Aberrant Albino and Achiasmat Visual Pathways: Noninvasive Electrophysiological Assessment
26. Clinical Psychophysical Techniques
27. Measurement of Contrast Sensitivity
28. Suppressive Rod-Cone Interaction
29. The Use of Fluorescein Angiography as an Adjunct to Electrophysiological Testing

VI: DATA ANALYSIS

  1. Experimental Design and Data Analyses in Vision Function Testing
  2. Analytical Techniques
  3. Reverse Correlation Methods
  4. Stimulus-Response Functions for the Scotopic b-Wave
  5. Kernel Analysis
  6. Measuring the Health of the Human Photoreceptors with the Leading Edge of the a-Wave

VII: PRINCIPLES OF CLINICAL TESTING

  1. Localizing Lesions in the Visual System
  2. Paired-Flash ERG Analysis of Rod Phototransduction and Adaptation
  3. Hyperabnormal (Supranormal) Electroretinographic Responses
  4. Technical Issues in Evaluating Patients for Therapeutic Trials

VIII: OTHER PROTOCOLS FOR RECORDING OF ERG AND SLOWER POTENTIALS, TECHNICAL ISSUES, AND AUXILIARY TESTING TECHNIQUES

  1. Early Receptor Potential
  2. Nonphotic Standing Potential Responses: Hyperosmolarity, Bicarbonate, and Diamox Responses
  3. Direct Current Electroretinogram
  4. The Oscillatory Potentials of the Electroretinogram
  5. Flicker Electroretinography
  6. Chromatic Recordings of Electroretinograms
  7. Adaptation Effects on the Electroretinogram
  8. Clinical Electrophysiological and Psychophysical Investigations into Color Defects
  9. Causes and Cures of Artifacts

IX: PRINCIPLES OF CLINICAL TESTING AND EVALUATION OF VISUAL DYSFUNCTION FROM DEVELOPMENTAL, TOXIC, AND ACQUIRED CAUSES

  1. Testing Levels of the Visual System
  2. Effects of High Myopia on the Electroretinogram
  3. Electrodiagnostic Testing in Malingering and Hysteria
  4. Developmental Amblyopia
  5. Visual Evoked Potentials in Cortical Blindness
  6. Drug Side Effects and Toxicology of the Visual System
  7. Mitochondrial Diseases

X: EVALUATION OF VASCULAR DISEASES, INFLAMMATORY STATES, AND TUMORS

  1. Diseases of the Middle Retina: Venous and Arterial Occlusions
  2. Acute Disorders of the Outer Retina, Pigment Epithelium, and Choroid
  3. Autoimmune Retinopathy, CAR and MAR Syndromes
  4. Ischemic Optic Neuropathy

XI: CLINICAL DESCRIPTIONS: RETINAL PIGMENT EPITHELIUM DISEASES

  1. Gyrate Atrophy of the Choroid and Retina
  2. Dominant Drusen
  3. Stargardt Disease
  4. Bietti’s Crystalline Dystrophy of the Cornea and Retina
  5. Leber Congenital Amaurosis
  6. Pattern Dystrophies
  7. Best Vitelliform Macular Dystrophy
  8. Sorsby’s Fundus Dystrophy

XII: DISEASES OF THE OUTER RETINA

  1. Choroideremia
  2. Retinitis Pigmentosa
  3. Cone Dystrophies and Degenerations
  4. Vitamin A Deficiency

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