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Retinal Degenerations Biology Diagnostics and Therapeutics 1st Edition by Joyce Tombran Tink, Colin Barnstable 1588296202 9781588296207

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Retinal Degenerations Biology Diagnostics and Therapeutics 1st Edition Joyce Tombran-Tink Digital Instant Download

Author(s): Joyce Tombran-Tink, Colin J. Barnstable
ISBN(s): 9781597451864, 159745186X
Edition: 1
File Details: PDF, 7.89 MB
Year: 2007
Language: english
SKU: EB-1223328 Category: Tags: ,

Retinal Degenerations Biology Diagnostics and Therapeutics 1st Edition by Joyce Tombran Tink, Colin Barnstable – Ebook PDF Instant Download/Delivery: 1588296202, 9781588296207

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ISBN 10: 1588296202

ISBN 13: 9781588296207

Author: Joyce Tombran-Tink, Colin J. Barnstable

For centuries, humans have tried to explain the complex process of vision and find effective treatments for eye diseases. Perhaps the oldest surviving record of ancient ophthalmic practices is the Babylonian code of Hammurabi that over 4000 years ago, mentioned fees for eye surgery―and penalties for unsuccessful operations that led to loss of the eye. Babylonian medicine was controlled by priests who directed the work of skilled surgeons. The earliest records of Egyptian medicine date from almost the same time. The Ebers Papyrus, dating back to more than 3500 years ago is a superbly preserved document in which a section outlines a relatively advanced system of diagnosis and treatment of various ocular pathologies. The text reveals that ancient Greek and Egyptian physicians prescribed “liver juice” for night blindness. This was obtained from roasted and crushed ox liver. We now know that their prescription contained a remarkable amount of vitamin A. It was only within the last century, however, that we have recognized the importance of vitamin A to the function of photoreceptors and visual acuity and that its deficiency can result in night blindness. Egyptian ophthalmological practices were held in high esteem in the ancient world and so were their medical institutes, called “peri-ankh,” which existed since the first dynasty. Herodotus, the fifth century BC Greek historian, comments on the specialization of the physicians: “Each physician treats just one disease.

Retinal Degenerations Biology Diagnostics and Therapeutics 1st Table of contents:

I. Living with Retinal Degeneration

  1. Coping With Retinal Degeneration
  2. Degenerative Diseases of the Retina
  3. Epidemiology of Age-Related Macular Degeneration Early in the 21st Century
  4. Leber Congenital Amaurosis
  5. Macular Degeneration
  6. Stargardt Disease
  7. X-Linked Juvenile Retinoschisis
  8. Retinal Degeneration in Usher Syndrome
  9. Mouse Models of RP
  10. Mechanisms Underlying Retinal Degenerations
  11. The Impact of Diabetes on Neuronal, Glial, and Vascular Cells of the Retina
  12. Statins and Age-Related Maculopathy
  13. The Role of Drusen in Macular Degeneration and New Methods of Quantification
  14. RPE Lipofuscin
  15. Genetic Modifiers That Affect Phenotypic Expression of Retinal Diseases
  16. X-Linked Retinal Dystrophies and Microtubular Functions Within the Retina
  17. Synaptic Remodeling in Retinal Degeneration

II. Developing Therapeutic Strategies for Retinal Degenerative Diseases

  1. On The Suppression of Photoreceptor Cell Death in Retinitis Pigmentosa
  2. Cell-Based Therapies to Restrict the Progress of Photoreceptor Degeneration
  3. Current Status of IPE Transplantation and Its Potential as a Cell-Based Therapy for Age-Related Macular Degeneration and Retinal Dystrophies
  4. Recent Results in Retinal Transplantation Give Hope for Restoring Vision
  5. Stem Cells and Retinal Transplantation
  6. Application of Encapsulated Cell Technology for Retinal Degenerative Diseases
  7. Effective Treatment for the Canine RPE65 Null Mutation, a Hereditary Retinal Dystrophy Comparable to Human Leber’s Congenital Amaurosis
  8. Neuroprotective Factors and Retinal Degenerations
  9. Carbonic Anhydrase Inhibitors as a Possible Therapy for RP17, an Autosomal Dominant Retinitis Pigmentosa Associated With the R14W Mutation, Apoptosis, and the Unfolded Protein Response

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Joyce Tombran Tink,Colin Barnstable,Retinal,Degenerations