The Art of Process Chemistry 1st Edition by Nobuyoshi Yasuda 3527324704 9783527324705

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ISBN 10: 3527324704

ISBN 13: 9783527324705

Author: Nobuyoshi Yasuda

Providing must-have knowledge for the pharmaceutical industry and process chemists in industry, this ready reference offers solutions for saving time and money and supplying — in a sustainable way — valuable products. Application-oriented and well structured, each chapter presents successful strategies for the latest modern drugs, showing how to provide very fast bulk quantities of drug candidates. Throughout, the text illustrates how all the key factors are interwoven and dependent on one another in creating optimized methods for optimal products.

The Art of Process Chemistry 1st Table of contents:

1 Efavirenz®, a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), and a Previous Structurally Related Development Candidate

1.1 First Drug Candidate 2

1.2 Efavirenz®

1.3 Conclusion

Acknowledgments

2 CCR5 Receptor Antagonist

2.1 Project Development

2.2 Chemistry Development

2.3 Conclusion

Acknowledgments

3 5α-Reductase Inhibitors – The Finasteride Story

3.1 Project Development

3.2 Chemistry Development

3.3 Conclusion

Acknowledgments

4 Rizatriptan (Maxalt®): A 5-HT1D Receptor Agonist

4.1 Project Development

4.2 Chemistry Development

4.3 Conclusion

Acknowledgments

5 SERM: Selective Estrogen Receptor Modulator

5.1 Project Development

5.2 Chemistry Development

5.3 Conclusion

Acknowledgments

6 HIV Integrase Inhibitor: Raltegravir

6.1 Project Development

6.2 Further Chemistry Development

6.3 Conclusion

Acknowledgments

7 Cyclopentane-Based NK1 Receptor Antagonist

7.1 Project Development Compound 1

7.2 Chemistry Development

Acknowledgments

8 Glucokinase Activator

8.1 Project Development

8.2 Chemistry Development

8.3 Conclusion

Acknowledgments

9 CB1R Inverse Agonist – Taranabant

9.1 Project Development

9.2 Further Project Development

9.3 Conclusion

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Tags: Nobuyoshi Yasuda, Art, Process, Chemistry