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The Hemopoietic Colony Stimulating Factors From Biology to Clinical Applications 1st Edition by Donald Metcalf, Nicos Anthony Nicola 9780521461580 0521461588

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The Hemopoietic Colony Stimulating Factors From Biology to Clinical Applications 1st Edition Donald Metcalf Digital Instant Download

Author(s): Donald Metcalf, Nicos Anthony Nicola
ISBN(s): 9780521461580
Edition: 1st
File Details: PDF, 9.20 MB
Year: 2006
Language: english
SKU: EB-2220964 Category: Tags: ,

The Hemopoietic Colony Stimulating Factors From Biology to Clinical Applications 1st Edition by Donald Metcalf, Nicos Anthony Nicola – Ebook PDF Instant Download/Delivery: 0521461588, 9780521461580 

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Product details:

ISBN 10: 0521461588

ISBN 13: 9780521461580 

Author: Donald Metcalf, Nicos Anthony Nicola

The colony-stimulating factors (CSFs) are the major regulators in the body of the production and activity of two types of white blood cells–granulocytes and macrophages. CSFs are used by clinicians to treat patients with damaged immune systems, for example, as a result of chemotherapy. This book provides a detailed and up-to-date account of the discovery of the CSFs, their structure, molecular biology and cellular receptors, the biology of the CSFs in vivo and in vitro, and their present and future clinical applications. Written by two of the pioneers in the discovery of CSFs, it is a clear and well illustrated survey of the history, current knowledge and future directions of this exciting field of investigation, and serves also as a guide to the more general areas of growth factor and cytokine research. It will prove an invaluable review for cell biologists interested in how growth factors act on the body, as well as for clinicians applying the fruits of modern biotechnology to improved patient care.

Table of contents:

 

Chapter 1 Historical Introduction

Chapter 2 General Introduction to Hemopoiesis

Chapter 3 Key Techniques in Analyzing Hemopoiesis

Chapter 4 Biochemistry of the Colony-Stimulating Factors

Chapter 5 Biochemistry of the Colony-Stimulating Factor Receptors

Chapter 6 Molecular Genetics of the Colony-Stimulating Factors and Their Receptors

Chapter 7 Biological Actions of the Colony-Stimulating Factors in vitro

Chapter 8 The Biology of Colony-Stimulating Factor Production, Degradation and Clearance

Chapter 9 Actions of the Colony-Stimulating Factors in vivo

Chapter 10 Role of the Colony-Stimulating Factors in Basal Hemopoiesis

Chapter 11 Actions of the Colony-Stimulating Factors in Resistance to Infections

Chapter 12 Role of the Colony-Stimulating Factors in Other Disease States

Chapter 13 The Colony-Stimulating Factors and Myeloid Leukemia

Chapter 14 Clinical Uses of the Colony-Stimulating Factors

Chapter 15 Conclusions

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Tags: Donald Metcalf, Nicos Anthony Nicola, Hemopoietic, Factors