The Innate Immune System A compositional and functional perspective 1st Edition by Tom Monie 9780081007587 0081007582

The Innate Immune System A compositional and functional perspective 1st Edition by Tom Monie – Ebook PDF Instant Download/Delivery: 9780081007587, 0081007582

Full download The Innate Immune System A compositional and functional perspective 1st Edition after payment

 

Product details:

ISBN 10: 0081007582

ISBN 13: 9780081007587

Author: Tom P. Monie

The Innate Immune System: A Compositional and Functional Perspective focuses on the components and functionality of the innate immune system, detailing how they work in their own right, and then progressing to cover their relevance to disease and how they interface with the adaptive response.

Despite the growing appreciation of the importance of the innate immune system, many classical immunology books still focus predominantly on the adaptive immune response. Not only is this unbalanced, but it fails to reflect the growing synergy between the activation and function of the innate response and the final nature of adaptive response. This book fills the gap in knowledge that is needed to fully understand and appreciate the topic.

• Provides a clear, but simple picture of the main principle of innate immunity and the interlink with adaptive responses
• Fulfills an unmet need in the area of innate immunity
• Gives a constructive and progressive approach to introducing and explaining the key players in the innate immune response
• Introduces and explains the key players in the innate immune response with a constructive and progressive approach
• Presents the components of the innate response and shows how these interrelated areas connect with one another from a functional perspective
• Enables the reader to gradually increase their level of understanding and knowledge without the risk of becoming confused, thereby ensuring they fully comprehend the integrated signaling pathways

Table of contents:

Section 1. A Snapshot of the Innate Immune System

1.1. A Brief History of Immunity

1.2. The Immune System—A Complex Defense System

1.3. Functional Elements on the Innate Immune Response

1.4. The Mucosa-Associated Innate Immune System

1.5. Additional Homeostatic Functions Involved in Innate Immune Responses

Section 2. Immune Cells and the Process of Pattern Recognition

2.1. The Cellular Basis of the Innate Immune System

2.2. Pattern Recognition Receptor Signaling Pathways

Section 3. Effector Mechanisms and Cellular Outputs

3.1. Cytokines

3.2. Acute Phase Proteins and the Acute Phase Response

3.3. Reactive Oxygen Species

3.4. Enzymatic Cascades and Enzymatic Activation

3.5. Cell Death

Section 4. Integrated Innate Immunity—Combining Activation and Effector Functions

4.1. The Detection of Bacterial Lipopolysaccharide

4.2. Interleukin 1β Is Produced Following Activation of the Inflammasome

4.3. The Innate Response to Bacterial Infection With Salmonella

4.4. Innate Recognition and the Response to the Influenza Virus

Section 5. Connecting the Innate and Adaptive Immune Responses

5.1. The Transcriptional Regulation of MHC Class I and II Genes

5.2. Complement and the Adaptive Immune Response

5.3. Autophagy and the Development of T and B Cells

5.4. The Dendritic Cell Is the Interface Between the Innate and the Adaptive Immune Response

5.5. Adjuvants, PRRs, and Vaccination

Section 6. The Innate Immune System in Health and Disease

61. Inflammation and Atherosclerosis

62. Rheumatoid Arthritis

6.3. Autoinflammatory Syndromes

6.4. Inflammatory Bowel Disease

6.5. Animal Models of Inflammatory Disorders

People also search:

what are the main components of the innate immune system

what is the role of the innate immune system

what are components of the innate immune system

the innate immune system includes

the innate immune system consists of

Tags: Tom Monie, Innate, Immune, System, compositional