The Role of Microtubules in Cell Biology Neurobiology and Oncology 1st Edition by Tito Fojo 1597453366 9781597453363

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Product details:

ISBN 10: 1597453366 

ISBN 13: 9781597453363

Author: Tito Fojo

“The Role of Microtubules in Cell Biology, Neurobiology, and Oncology presents the first comprehensive exploration of the dynamic potential of microtubules as anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available. Among the topics examined in this volume are compounds that interact with tubulin, mechanisms and regulation by microtubule-associated proteins and drugs, MAPs, the tubulin superfamily, destabilizing agents, and neurodegenerative diseases.”–Jacket

The Role of Microtubules in Cell Biology Neurobiology and Oncology 1st Table of contents:

Overview of Tubulin-Interacting Compounds and Their Effects on Microtubule Assembly

Molecular Mechanisms of Microtubule-Acting Cancer Drugs

Microtubule Dynamics

Microtubule-Associated and Interacting Proteins

Post-Translational Modifications of Tubulin

Tubulin Isotypes

The Tubulin Superfamily

Tubulin Proteomics in Cancer

Tubulin and Microtubule Structures

Microtubule-Destabilizing Agents

Molecular Interactions of Colchicine and Related Compounds with Tubulin

Covalent-Binding Antimicrotubule Agents

Microtubule-Stabilizing Agents

Mechanisms of Drug Resistance in Microtubule-Interfering Agents

Resistance to Microtubule-Targeting Drugs

Clinical Applications of Microtubule-Stabilizing Agents in Oncology

Investigational Anticancer Agents Targeting Microtubules

Microtubule-Damaging Agents and Apoptosis

Microtubule-Targeting Agents and Tumor Vasculature

Microtubules in Neurodegenerative Diseases

Structure, Function, and Regulation of Tau Protein

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Tags: Tito Fojo, Microtubules, Biology, Neurobiology