Translational Pain Research From Mouse to Man 1st Edition by Lawrence Kruger, Alan Light 9781439812099 1439812098
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Product details:
ISBN 10: 1439812098
ISBN 13: 9781439812099
Author: Lawrence Kruger, Alan R Light
One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical
Table of contents:
Chapter 1 Painful Multi-Symptom Disorders: A Systems Perspective
Chapter 2 Neurotrophic Factors and Nociceptor Sensitization
Chapter 3 The Role of Visceral Afferents in Disease
Chapter 4 Cancer Pain: From the Development of Mouse Models to Human Clinical Trials
Chapter 5 Therapeutic Targeting of Peripheral Cannabinoid Receptors in Inflammatory and Neuropathic Pain States
Chapter 6 Molecular Strategies for Therapeutic Targeting of Primary Sensory Neurons in Chronic Pain Syndromes
Chapter 7 Transgenic Mouse Models for the Tracing of “Pain” Pathways
Chapter 8 Cytokines in Pain
Chapter 9 Glial Modulation in Pain States: Translation into Humans
Chapter 10 On the Role of ATP-Gated P2X Receptors in Acute, Inflammatory, and Neuropathic Pain
Chapter 11 Myalgia and Fatigue: Translation from Mouse Sensory Neurons to Fibromyalgia and Chronic Fatigue Syndromes
Chapter 12 Reflex Autonomic Responses Evoked by Group III and IV Muscle Afferents
Chapter 13 Central Pain as a Thalamocortical Dysrhythmia: A Thalamic Efference Disconnection?
Chapter 14 What Can Neuroimaging Tell Us about Central Pain?
Chapter 15 Human Brain Imaging Studies of Chronic Pain: Translational Opportunities
Chapter 16 Consideration of Pharmacokinetic Pharmacodynamic
Chapter 17 Large Animal Models for Pain Therapeutic Development
Chapter 18 Drug Discovery and Development for Pain
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Tags: Lawrence Kruger, Alan Light, Translational, Research