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Transmembrane Transporters 1st Edition by Michael Quick 0471065137 9780471065135

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Transmembrane Transporters 1st Edition Michael W. Quick Digital Instant Download

Author(s): Michael W. Quick
ISBN(s): 9780471065135, 0471065137
Edition: 1
File Details: PDF, 4.49 MB
Year: 2002
Language: english
SKU: EB-928928 Category: Tag:

Transmembrane Transporters 1st Edition by Michael Quick – Ebook PDF Instant Download/Delivery: 0471065137, 9780471065135

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Product details:

ISBN 10: 0471065137 

ISBN 13: 9780471065135

Author: Michael W. Quick

A must-have far-reaching text that provides readers with a state-of-the-art molecule update on transmembrane transporters, focusing on the methodological approaches currently employed to better understand how transporters work and how they can be used in cutting edge therapies. Each chapter begins with an overview of the importnat biological questions presently being considered in their field, then presents scientific approaches to address these questions. In explaining approaches, the authors cover bench-top protocols, conceptual frameworks, data obtained, and pitfalls common to the techniques.

Table of contents:

  1. Families of Transporters and Their Classification

  2. Yeast as a Model System for Studying Glucose Transport

  3. Neurotransmitter Transporters of Drosophila

  4. Transgenic Mice in Monoamine Transporter Research

  5. Searching for Novel Genetic Variation in Neurotransmitter Transporters

  6. Nonviral Gene Transfer Allows Up- and Down-Expression of the Brain Serotonin Transporter with Functional Consequences

  7. Methods in Studying the Regulation and Trafficking of Transmembrane Transporters

  8. Chemical Modification Strategies for Structure-Function Studies

  9. Methanethiosulfonate Reagent Accessibility Studies, Cysteine-Scanning Mutagenesis, Protein Overexpression, and Functional Reconstitution: A Strategy for Studying the Structure/Function Relationships within the Mitochondrial Citrate Transport Protein

  10. Peptide Mapping of Dopamine Transporter Ligand and Substrate Interaction Sites

  11. Mass Spectrometry of Membrane Transport Proteins

  12. Amperometric Recording of Amphetamine-Induced Dopamine Efflux

  13. Voltage Clamp and Fluorometric Techniques for Studying Glutamate Transporter Function

  14. Studies of Glial Glutamate Transporters in Hippocampal Microcultures

  15. Imaging Monoamine Transporters in the Brain

  16. Measuring and Modeling the Spatiotemporal Profile of GABA at the Synapse

 

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Tags: Michael Quick, Transmembrane, Transporters