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Transporters as Drug Carriers Structure Function Substrates 1st Edition by Gerhard Ecker, Peter Chiba, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers 3527316612 9783527316618

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Transporters as Drug Carriers Structure Function Substrates Methods and Principles in Medicinal Chemistry 1st Edition Gerhard Ecker Digital Instant Download

Author(s): Gerhard Ecker, Peter Chiba, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
ISBN(s): 9783527316618, 3527316612
Edition: 1
File Details: PDF, 4.94 MB
Year: 2009
Language: english
SKU: EB-1705266 Category: Tags: , , , ,

Transporters as Drug Carriers Structure Function Substrates 1st Edition by Gerhard Ecker, Peter Chiba, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers – Ebook PDF Instant Download/Delivery: 3527316612, 9783527316618

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ISBN 10: 3527316612

ISBN 13: 9783527316618

Author: Gerhard Ecker, Peter Chiba, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers

Dieser Band aus der Reihe “Methods and Principles in Medicinal Chemistry” beleuchtet die Rolle molekularer Wirkstofftransporter im Kontext der Therapieoptimierung und der Aufklärung von Wirkstoffresistenzen. Alle bekannten Transporterklassen (vom Mikroorganismus bis zum Menschen) werden vorgestellt.

Transporters as Drug Carriers Structure Function Substrates 1st Table of contents:

Part One: Human Transporter Families? Structure, Function, Physiology
1. The ABC Transporters: Structural Insights into Drug Transport (Robert C. Ford, Alhaji B. Kamis, Ian D. Kerr, and Richard Callaghan)
2. Biochemistry, Physiology, and Pharmacology of Nucleoside and Nucleobase Transporters (Marȧl Pastor-Anglada, Miriam Molina-Arcas, Pedro Cano-Soldado, and Francisco Javier Casado)
3. Organic Anion Transporting Polypeptides (Oatps/OATPs) (Mine Yarim and Meric Koksal)
4. CNS-Transporters as Drug Targets (Klaus Gundertofte)
Part Two: Drug Transport in Microorganisms and Fungi
5. Bacterial Multidrug Transporters: Molecular and Clinical Aspects (Olga Lomovskaya, Helen I. Zgurskaya, and Keith Bostian)
6. Membrane Transporters in Pleiotropic Drug Resistance and Stress Response in Yeast and Fungal Pathogens (Tobias Schwarzmuller, Cornelia Klein, Martin Valachovic, Walter Glaser, and Karl Kuchler)
Part Three: Structure Activity Relationship Studies on ABC Transporter
7. QSAR Studies on ABC Transporter? How to Deal with Polyspecificity (Gerhard F. Ecker)
8. Drug Transporter Pharmacophores (Sean Ekins)
Part Four: Transporters and ADME
9. Biological Membranes and Drug Transport (Gert Fricker)
10. Transport at the Blood-Brain Barrier (Winfried Neuhaus and Christian R. Noe)
11. Bile Canalicular Transporters (Dirk R. de Waart and Ronald P.J. Oude Elferink)
12. Interplay of Drug Metabolizing Enzymes and ABC Transporter (Walter Jager)
13. ABC Transporters? From Targets to Antitargets? (Gerhard F. Ecker and Peter Chiba)
Part Five: A Systems View of Drug Transport
14. A Systems Biology View of Drug Transporters (Sean Ekins and Dana L. Abramovitz)
15. Drug Transporters in Health and Disease (Barbara Bennani-Bat̐i and Christian R. Noe)

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Tags: Gerhard Ecker, Peter Chiba, Raimund Mannhold, Transporters