Understanding leukemias lymphomas and myelomas 2nd Edition by Tariq I Mughal, John Goldman, Sabena Mughal ISBN 1841846945 9781841846941

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ISBN 10: 1841846945 
ISBN 13: 9781841846941
Author: Tariq I Mughal, John Goldman, Sabena Mughal

A brand-new edition of the bestselling guide to hematologic malignancies. An international team of contributors come together to present all clinically relevant aspects of leukemias, lymphomas, and myelomas. Using clear terminology, the book discusses salient features, diagnostic procedures, prognosis, and treatments for these cancers. Following on the successful steps of the first edition, this Second Edition covers: various types of leukemias, lymphomas, and myelomas utilizing stem cell transplantation side-effects of various treatments future prospects for leukemia, lymphoma, and myeloma targeted therapies and history of the cancers information and support sources for patients.

Understanding leukemias lymphomas and myelomas 2nd Table of contents:

1 Introduction to Blood Cancers
What Happens in Cancer?
Molecular Basis of Cancer
Genetics and Genomics of Cancer
Cancer Pathogenesis
Cell Cycle
2 Myths and Facts About Blood and Stem Cells
Hematopoiesis, Stem Cells, and Progenitor Cells
Plasticity of Stem Cells
Hematopoietic Growth Factors
Components of Blood
Immune Response
The Lymphatic System
3 What Happens in Leukemias, Lymphomas, and Myelomas?
History of Blood Cancers
What Happens in Leukemias, Lymphomas, and Myelomas?
Blood Cancer Biology and Cytogenetics
How Prevalent Are Leukemia, Lymphoma, and Myeloma?
What Causes Leukemia, Lymphoma, and Myeloma?
Risks From Infections
Burkitt’s Lymphoma
Adult T-cell Leukemia/lymphoma and HIV-associated Lymphoma
Gastric Lymphoma and Helicobacter Pylori Infection
Risks From Radiation
Risks From Chemicals
Risks From Genetic Factors
Risks From Dietary Factors
4 Different Types of Leukemias, Lymphomas, and Myelomas
Leukemias
Acute Myeloid Leukemia
Prognostic and Predictive Factors
Acute Lymphoblastic Leukemia
Prognostic and Predictive Factors
Chronic Myeloid Leukemia
Staging Systems and Prognostic Factors
Juvenile Myelomonocytic Leukemia
Chronic Myelomonocytic Leukemia
Myeloproliferative Disorders
Chronic Lymphocytic Leukemia
Staging Systems and Prognostic Factors
Prolymphocytic Leukemia
Large Granular Lymphocytic Leukemia
Hairy Cell Leukemia
Adult T-cell Leukemia/lymphoma
Myelodysplastic Syndromes
Staging Systems and Prognostic Factors
Lymphomas
Hodgkin Lymphoma (Hl)
Nodular Sclerosis Classical Hl (Chl)
(Nodular Lymphocyte-Predominant Classic Hodgkin Lymphoma
Mixed Cellularity Classic Hodgkin Lymphoma (Mchl)
Lymphocyte-Depleted Classical Hodgkin Lymphoma
Lymphocyte-Rich Classic Hodgkin Lymphoma
Non-Hodgkin Lymphoma
Lymphoblastic Lymphoma
Diffuse Large B-cell Lymphoma
Follicular Lymphoma
Mucosa-Associated Lymphoid Tissue Lymphoma
Mantle Cell Lymphoma (Mcl)
Burkitt’s Lymphoma
Peripheral T-cell Lymphoma
Anaplastic Large T-/Null-cell Lymphoma
Adult T-cell Leukemia/lymphoma
Mycosis Fungoides/Sëzary Syndrome
Primary Cerebral Lymphoma
Myelomas
Multiple Myeloma
Monoclonal Gammopathy of Undetermined Significance
Waldenström’s Macroglobulinemia
Plasma Cell Leukemia
Plasmacytoma
Poems Syndrome
Primary Amyloidosis
5 Diagnosis of Leukemia, Lymphoma, and Myeloma
Leukemia
Initial Presentation
Diagnosis
Lymphomas
Initial Presentation
Diagnosis
Myelomas
Initial Presentation
Diagnosis
6 the Patient and the Specialist
Communication Between the Patient and the Specialist
Communicating With the Young Patient
Communicating With the Adult Patient
Leukemias
Lymphomas
Myelomas
Communicating With Older Patients
Concluding Remarks
7 General Management of Blood Cancers
Introduction
General Supportive Treatment
General Aspects of Treatment of Blood Cancers
Vascular Access
Bacterial Infection
Viral Infection
Fungal Infection
Tumor Lysis Syndrome
Drug Resistance
Leukapheresis
Hematopoietic Growth Factors
Significance of Neutropenia Related to Cancer Treatments
Significance of Anemia Related to Cancer and Cancer Treatment
Radiotherapy
Clinical Trials
8 Specific Therapy for Leukemias
Acute Myeloid Leukemia (Aml)
Remission Induction
Consolidation (Post-Remission) Therapy
Treatment of Patients Older Than 60 Years of Age With Aml
Other Investigational Therapies in Aml
Acute Lymphoblastic Leukemia (All)
Remission Induction
Post-Remission Therapy
Treatment of Relapsed All
Chronic Myeloid Leukemia
Imatinib Mesylate
Interferon-Alfa
Hydroxyurea
Future Approaches
Chronic Lymphocytic Leukemia
Prolymphocytic Leukemia (Pll)
Large Granular Lymphocytic (Lgl) Leukemia
Hairy Cell Leukemia
Adult T-cell Leukemiatymphoma (Atll)
Myelodysplastic Syndrome
Myeloproliferative Neoplasms
9 Specific Therapy for Lymphomas
Hodgkin Lymphoma (Hl)
Early-Stage Hodgkin Lymphoma
Advanced Stage Hodgkin Lymphoma
Relapsed and/or Refractory Hodgkin Lymphoma
Hodgkin Lymphoma in Pregnancy
Non-Hodgkin Lymphoma
Low-Grade Lymphomas
Follicular Lymphoma
Small Lymphocytic Lymphoma
Mantle Cell Lymphoma (Mcl)
Relapsed and/or Refractory Mantle Cell Lymphoma
High-Grade Lymphomas
Diffuse Large B-cell Lymphoma
Relapse and/or Refractory Diffuse Large B-cell Lymphoma
Early-Stage Diffuse Large B-cell Lymphoma
Burkitt’s Lymphoma
Lymphoblastic Lymphoma
Peripheral T-/Natural Killer (NK)-cell Neoplasms
Peripheral T-cell Lymphoma (Ptcl), Not Otherwise Characterized
Anaplastic Large Cell Lymphoma
Adult T-cell Lymphoma/leukemia (Atl)
Extranodal Lymphomas
Mucosa-Associated Lymphoid Tissue (Malt) Lymphoma
Primary Cns Lymphomas (Pcnsl)
Testicular Lymphomas
Cutaneous Lymphomas
Mycosis Fungoides/Sézary Syndrome
10 Specific Current Therapy for Myelomas
Multiple Myeloma
Supportive Therapy
Newly Diagnosed Multiple Myeloma
Relapsed and Refractory Multiple Myeloma
High-Dose Therapy and Autologous Sct
Monoclonal Gammopathy of Unknown Significance (Mgus)
Smoldering Multiple Myeloma
Plasmacytomas
Plasma Cell Leukemia
WaldenstrÖm’s Macroglobulinemia(Wm)
Primary Amyloidosis
Specific Supportive Care
Specific Amyloidoisis Therapy
11 Current Role of Stem Cell Transplantation for Leukemias, Lymphomas, and Myelomas
Introduction
Type of Stem Cell Transplant
Immunological Barriers
Selection of the Donor
Graft-Versus-Host Disease
Graft-Versus-Tumor Effect
Hemopoietic Chimerism
Sources of Hematopoietic Stem Cells
Bone Marrow
Peripheral Blood
Umbilical Cord
Preparative (“Conditioning”) Regimens
Non-Myeloablative Transplants
Management of Patients Undergoing Sct
What Happens to the Donor?
What Happens to the Recipient?
Management of Relapse and Minimal Residual Disease (Mrd) After Sct
Clinical Results of Stem Cell Transplantation for Hematological Cancers
Acute Myeloid Leukemia
Acute Lymphoblastic Leukemia
Chronic Myeloid Leukemia
Chronic Lymphocytic Leukemia (Cll)
Myelodysplastic Syndrome
Non-Hodgkin Lymphomas
Hodgkin Lymphoma
Myeloma
12 Principal Side-Effects of the Treatment of Leukemias, Lymphomas, and Myelomas
Acute Side-Effects
Nausea and Vomiting
Oral Complications
Hair Loss (Alopecia)
Bone Marrow Suppression
Nerve Damage (Neuropathy)
Kidney Problems (Nephropathy)
Liver Problems (Hepatotoxicity)
Heart Problems (Cardiotoxicity)
Bone Problems (Bone Necrosis)
Psychological Issues
Late Side-Effects
Infertility
Second Cancers
Late-Effects Related to Chronic Graft-Versus-Host Disease (Gvhd) in Allogeneic Sct Recipients
Radiotherapy-Related Effects

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Tags: Tariq I Mughal, John Goldman, Sabena Mughal, leukemias, lymphomas